To determine the incidence and relative risk (RR) of cancer in children with Beckwith-
Wiedemann syndrome (BWS), children with BWS were followed up from birth until death …

Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

Abstract Background Beckwith-Wiedemann syndrome (BWS) is a cancer predisposition
syndrome caused by defects on chromosome 11p15. 5. The quantitative cancer risks in …

Abstract Beckwith–Wiedemann Syndrome (BWS) results from mutations or epigenetic
events involving imprinted genes at 11p15. 5. Most BWS cases are sporadic and uniparental …

PURPOSE: Children with Beckwith-Wiedemann syndrome (BWS) are at increased risk for
developing Wilms' tumor (WT). We reviewed the National Wilms Tumor Study Group …

Beckwith–Wiedemann syndrome (BWS) is an overgrowth syndrome associated with
macroglossia, abdominal wall defects, ear anomalies, and an increased risk for embryonic …

Background: Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated
with an increased risk of pediatric tumors. The underlying molecular abnormalities may be …

Objective To compare tumor risk in the 4 Beckwith-Wiedemann syndrome (BWS) molecular
subgroups: Imprinting Control Region 1 Gain of Methylation (ICR1-GoM), Imprinting Control …

There is strong evidence for an association between overgrowth disorders such as Beckwith–
Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also …

Constitutional molecular defects are known to play a role in oncogenesis, as shown by the
increased incidence of embryonic cancers in children with Beckwith–Wiedemann syndrome …