An integrated double-filtration microfluidic device for detection of extracellular vesicles from urine for bladder cancer diagnosis

LG Liang, YF Sheng, S Zhou, F Inci, L Li… - … Vesicles: Methods and …, 2017 - Springer
Extracellular vesicles (EVs) are present in a variety of bodily fluids and they play an
important role in cellular communications and signal transduction mechanisms. Studies …

[HTML][HTML] An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer

LG Liang, MQ Kong, S Zhou, YF Sheng, P Wang… - Scientific reports, 2017 - nature.com
Extracellular vesicles (EVs), including exosomes and microvesicles, are present in a variety
of bodily fluids, and the concentration of these sub-cellular vesicles and their associated …

Extracellular Vesicles as Potential Bladder Cancer Biomarkers: Take It or Leave It?

A Teixeira-Marques, C Lourenço, MC Oliveira… - International Journal of …, 2023 - mdpi.com
Bladder cancer (BC) is the 10th most frequently diagnosed cancer worldwide. Although
urine cytology and cystoscopy are current standards for BC diagnosis, both have limited …

[HTML][HTML] Isolation-free measurement of single urinary extracellular vesicles by imaging flow cytometry

L Wu, WW Woud, CC Baan, DA Hesselink… - … , Biology and Medicine, 2023 - Elsevier
Urinary extracellular vesicles (uEVs) are promising biomarkers for various diseases.
However, many tools measuring uEVs rely on time-consuming uEV isolation methods, which …

[HTML][HTML] Urinary extracellular vesicles: a rising star in bladder cancer management

F Urabe, T Kimura, K Ito, Y Yamamoto… - Translational …, 2021 - ncbi.nlm.nih.gov
Clinically, the detection of bladder cancer (BCa) typically requires cystoscopy, which is
potentially harmful and sometimes accompanied by adverse effects. Thus, new biomarkers …

Single extracellular vesicle analysis performed by imaging flow cytometry and nanoparticle tracking analysis evaluate the accuracy of urinary extracellular vesicle …

M Droste, T Tertel, S Jeruschke, R Dittrich… - International journal of …, 2021 - mdpi.com
Small extracellular vesicles isolated from urine (uEVs) are increasingly recognized as
potential biomarkers. Meanwhile, different uEV preparation strategies exist. Conventionally …

Bladder cancer diagnosis and follow-up: the current status and possible role of extracellular vesicles

E Oeyen, L Hoekx, S De Wachter, M Baldewijns… - International journal of …, 2019 - mdpi.com
Diagnostic methods currently used for bladder cancer are cystoscopy and urine cytology.
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …

[HTML][HTML] Polyethylene glycol-based isolation of urinary extracellular vesicles, an easily adoptable protocol

AD Singh, S Patnam, A Manocha, L Bashyam… - MethodsX, 2023 - Elsevier
Urine is a highly advantageous biological specimen for biomarker research and is a non-
invasive source. Most of the urinary biomarkers are non-specific, volatile and need extensive …

Pre-analytical handling conditions and protein marker recovery from urine extracellular vesicles for bladder cancer diagnosis

J Lee, E Kim, J Park, S Choi, MS Lee, J Park - Plos one, 2023 - journals.plos.org
Extracellular vesicles (EVs) contain a variety of biomolecules and provide information about
the cells that produce them. EVs from cancer cells found in urine can be used as biomarkers …

Detection and investigation of extracellular vesicles in serum and urine supernatant of prostate cancer patients

S Salvi, E Bandini, S Carloni, V Casadio, M Battistelli… - Diagnostics, 2021 - mdpi.com
Prostate Cancer (PCa) is one of the most frequently identified urological cancers. PCa
patients are often over-diagnosed due to still not highly specific diagnostic methods. The …