Intranasal oxytocin may improve high-level social cognition in schizophrenia, but not social cognition or neurocognition in general: a multilevel bayesian meta …

PC Bürkner, DR Williams, TC Simmons… - Schizophrenia …, 2017 - academic.oup.com
While there is growing interest in the potential for intranasal oxytocin (IN-OT) to improve
social cognition and neurocognition (ie, nonsocial cognition) in schizophrenia, the extant …

A 12-week randomized controlled trial of twice-daily intranasal oxytocin for social cognitive deficits in people with schizophrenia

LF Jarskog, CA Pedersen, JL Johnson, RM Hamer… - Schizophrenia …, 2017 - Elsevier
Social cognition is impaired in people with schizophrenia and these deficits are strongly
correlated with social functioning. Oxytocin is a hypothalamic peptide that contributes to …

[PDF][PDF] Intranasal oxytocin mechanisms can be better understood, but its effects on social cognition and behavior are not to be sniffed at

DS Quintana, JD Woolley - Biol Psychiatry, 2016 - academia.edu
The administration of intranasal oxytocin (IN-OT) has demonstrated a wide range of effects
on social behavior and cognition, which has led to its proposed use as a treatment for …

Effects of oxytocin on empathy, introspective accuracy, and social symptoms in schizophrenia: A 12-week twice-daily randomized controlled trial

T Halverson, LF Jarskog, C Pedersen, D Penn - Schizophrenia research, 2019 - Elsevier
The effects of intranasal oxytocin, a neuropeptide involved in prosocial behavior and
modulation of neural networks underlying social cognition and emotion regulation, have …

Intranasal oxytocin for negative symptoms of schizophrenia: systematic review, meta-analysis, and dose-response meta-analysis of randomized controlled trials

M Sabe, N Zhao, A Crippa, GP Strauss… - International Journal of …, 2021 - academic.oup.com
Background Negative symptoms are a core aspect of psychopathology in schizophrenia.
Currently available pharmacological agents have proven minimally efficacious for …

Effects of intranasal oxytocin on symptoms of schizophrenia: A multivariate Bayesian meta-analysis

DR Williams, PC Buerkner - Psychoneuroendocrinology, 2017 - Elsevier
Schizophrenia is a heterogeneous disorder in which psychiatric symptoms are classified into
two general subgroups—positive and negative symptoms. Current antipsychotic drugs are …

Heterogeneity in response to repeated intranasal oxytocin in schizophrenia and autism spectrum disorders: A meta‐analysis of variance

D Martins, M Paduraru… - British Journal of …, 2022 - Wiley Online Library
Intranasal oxytocin (OT) has been suggested as a putative adjunctive treatment for patients
with schizophrenia and autism spectrum disorders (ASD). Here, we examine available …

Adjunctive intranasal oxytocin for schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials

W Zheng, XM Zhu, QE Zhang, XH Yang, DB Cai… - Schizophrenia …, 2019 - Elsevier
Objective Findings on the efficacy of intranasal oxytocin (IN-OT) in schizophrenia have been
inconsistent. This meta-analysis of double-blind randomized controlled trials (RCTs) …

Oxytocin administration enhances controlled social cognition in patients with schizophrenia

JD Woolley, B Chuang, O Lam, W Lai… - …, 2014 - Elsevier
Background Individuals with schizophrenia have functionally significant deficits in automatic
and controlled social cognition, but no currently available pharmacologic treatments reduce …

Intranasal oxytocin reduces psychotic symptoms and improves Theory of Mind and social perception in schizophrenia

CA Pedersen, CM Gibson, SW Rau, K Salimi… - Schizophrenia …, 2011 - Elsevier
Oxytocin has numerous prosocial and antipsychotic-like effects in animals. Prosocial effects
of acute intranasal oxytocin administration have also been reported in human subjects. We …