Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …

Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …

Downregulation of brain-derived neurotrophic factor (BDNF) in the cortex occurs early in the
progression of Alzheimer's disease (AD). Since BDNF plays a critical role in neuronal …

An emerging body of data suggests that the early onset of Alzheimer's disease (AD) is
associated with decreased brain-derived neurotrophic factor (BDNF). Because BDNF plays …

Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Brain-derived neurotrophic factor (BDNF) is a versatile neurotrophic factor that has been
implicated in cell survival, cell differentiation, axonal growth, and activity-dependent synaptic …

Alzheimer's disease (AD) is a senile dementia characterized by amyloid plaques,
neurofibrillary tangles, and synaptic and cell loss. The “amyloid cascade” hypothesis …

In Alzheimer's disease, soluble tau accumulates and deposits as neurofibrillary tangles
(NFTs). However, a precise toxic mechanism of tau is not well understood. We hypothesized …

Brain-derived neurotrophic factor (BDNF) plays pivotal roles in neuronal function. The
cleaved–mature–form of BDNF (mBDNF), predominantly expressed in adult brains, critically …

Introduction Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the
most common cause of dementia among the elderly population. AD is accompanied with the …