Neuroinflammation is an essential mechanism involved in the pathogenesis of
subarachnoid hemorrhage (SAH)-induced brain injury. Recently, Netrin-1 (NTN-1) is well …

Abstract Netrin‐1 (NTN‐1) is a novel drug to alleviate early brain injury following
subarachnoid haemorrhage (SAH). However the molecular mechanism of NTN‐1‐mediated …

Background Netrin-1 functions largely via combined receptors and downstream effectors.
Evidence has shown that astrocytes express netrin-1 receptors, including DCC and …

Neuronal apoptosis is a crucial pathological process in early brain injury after subarachnoid
hemorrhage (SAH). The effective therapeutic strategies to ameliorate neuronal apoptosis …

Oxidative stress and neuroinflammation are two major causes leading to early brain injury
after subarachnoid hemorrhage (SAH). Nuclear factor E2-related factor 2 (Nrf2) is a critical …

Background Neuroinflammation and blood-brain barrier (BBB) disruption are two vital
mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Recently …

Background Netrin‐1 (NTN‐1) has been established to be a novel intrinsic regulator of
blood‐brain barrier (BBB) maintenance. This study was carried out to investigate the …

Background: Subarachnoid hemorrhage (SAH) is a devastating disease which leads to high
morbidity and mortality. Recent studies have indicated that, never in mitosis gene A-related …

Introduction The current approaches that are used to treat ischemic stroke suffer from poor
targeting, lack of effectiveness, and potential off-target effects, necessitating the …

Neuroinflammation remains the primary cause of morbidity and mortality in stroke-induced
secondary brain injury. The NOD-like receptor pyrin 3 (NLRP3) inflammasome is involved in …