The antiinflammatory and antiapoptotic effects of chondroitin sulfate (CS) are being used to
treat osteoarthritis. Recent evidence has revealed that those peripheral effects of CS may …

Chondroitin sulfate proteoglycan (CSPG), a matrix protein that occurs naturally in the central
nervous system (CNS), is considered to be a major inhibitor of axonal regeneration and is …

Chondroitin sulfate proteoglycans (CSPGs) are widely expressed in the normal central
nervous system, serving as guidance cues during development and modulating synaptic …

Chondroitin sulphate proteoglycan (CSPG) inhibits axonal regeneration in the central
nervous system (CNS) and its local degradation promotes repair. We postulated that the …

The extracellular matrix (ECM) of the central nervous system (CNS) occupies a large part of
the neural tissue. It serves a variety of functions ranging from support of cell migration and …

Chondroitin sulfate (CS) is a glucosaminoglycan (GAG) currently used for the treatment of
osteoarthritis because of its antiinflammatory and antiapoptotic actions. Recent evidence …

Biochemistry of chondrotin sulphate• Mechanism of action of chondroitin sulphate‐Effect of
chondroitin sulphate on the chondrocyte‐Effect of chondroitin sulphate on the synovial …

The extracellular matrix of the central nervous system is an interconnected network of
proteins and sugars. It is crucial for homeostasis, but its remodeling in neurological diseases …

Chondroitin sulfate proteoglycans (CSPGs) consist of a core protein and glycosaminoglycan
(GAG) chains. There is enormous structural diversity among CSPGs due to variation in the …

Publisher Summary The central nervous system (CNS) is a rich and complex source of
proteins modified with chondroitin/dermatan sulfate (CS/DS) chains. During brain …