Chondroitin sulfate-based biomaterials for tissue engineering

HJ Kwon, Y Han - Turkish Journal of Biology, 2016 - journals.tubitak.gov.tr
Chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) that is usually found
attached to proteins as part of a proteoglycan. The use of CS-based biomaterials in the field …

[HTML][HTML] Chondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1β-stimulated chondrocytes–study in hypoxic alginate bead cultures

F Legendre, C Baugé, R Roche, AS Saurel… - Osteoarthritis and …, 2008 - Elsevier
OBJECTIVE: To determine the effect of avian chondroitin sulfate (CS) on interleukin-1β (IL-
1β)-induced expression of genes related to catabolic, anabolic and inflammatory aspects in …

An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

MB Keough, JA Rogers, P Zhang, SK Jensen… - Nature …, 2016 - nature.com
Remyelination is the generation of new myelin sheaths after injury facilitated by processes of
differentiating oligodendrocyte precursor cells (OPCs). Although this repair phenomenon …

Liposomal formulation of chondroitin sulfate enhances its antioxidant and anti-inflammatory potential in L929 fibroblast cell line

O Craciunescu, L Moldovan, M Moisei… - Journal of liposome …, 2013 - Taylor & Francis
Liposomes have the capacity to be used as efficient, biodegradable and nontoxic carriers of
bioactive molecules and are able to better control their delivery at the site of interest. The …

Comparative analyses of pharmaceuticals or food supplements containing chondroitin sulfate: are their bioactivities equivalent?

A Stellavato, OF Restaino, V Vassallo, R Finamore… - Advances in …, 2019 - Springer
Introduction Oral supplementation of chondroitin sulfate (CS) and glucosamine (GlcN),
symptomatic slow-acting molecules, is recommended by European Society for Clinical and …

Preparation of low molecular weight chondroitin sulfates, screening of a high anti-complement capacity of low molecular weight chondroitin sulfate and its biological …

L Li, Y Li, D Feng, L Xu, F Yin, H Zang, C Liu… - International Journal of …, 2016 - mdpi.com
Chondroitin sulfate (CS) plays important roles in the complement system. However, the CS
structure is complicated due to different sources and the number and positions of sulfate …

[HTML][HTML] Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stress

L Lippiello - Osteoarthritis and cartilage, 2003 - Elsevier
Objective: To test the hypothesis that chondrocytes are more responsive to the
chondroprotective agents, glucosamine (glcN) and chondroitin sulfate (CS), under in vitro …

Importance of pharmaceutical composition and evidence from clinical trials and pharmacological studies in determining effectiveness of chondroitin sulphate and …

KD Rainsford - Journal of Pharmacy and Pharmacology, 2009 - academic.oup.com
Objectives Chondroitin sulphate (CS) has attracted much interest over the past two decades
or so as a biological agent for use in the relief of pain and joint symptoms in osteoarthritis …

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination

LW Lau, MB Keough, S Haylock‐Jacobs… - Annals of …, 2012 - Wiley Online Library
Objective: Failure of remyelination is a critical impediment to recovery in multiple sclerosis
(MS). Chondroitin sulfate proteoglycans (CSPGs) have been reported to accumulate in MS …

Alterations in sulfated chondroitin glycosaminoglycans following controlled cortical impact injury in mice

JH Yi, Y Katagiri, B Susarla, D Figge… - Journal of …, 2012 - Wiley Online Library
Chondroitin sulfate proteoglycans (CSPGs) play a pivotal role in many neuronal growth
mechanisms including axon guidance and the modulation of repair processes following …