Diagnosis and management of immune checkpoint inhibitor‐associated renal toxicity: illustrative case and review

ME Sise, H Seethapathy, KL Reynolds - The Oncologist, 2019 - academic.oup.com
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies directed at negative
regulatory components on T cells, such as cytotoxic T lymphocyte‐associated antigen 4 …

Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury

B Sprangers, DE Leaf, C Porta, MJ Soler… - Nature Reviews …, 2022 - nature.com
Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors
(ICIs) have had an overwhelming impact on cancer treatment. Use of these agents in …

Kidney biopsy should be performed to document the cause of immune checkpoint inhibitor–associated acute kidney injury: CON

V Gutgarts, IG Glezerman - Kidney360, 2020 - journals.lww.com
Immune checkpoint inhibitors (ICPis) have revolutionized the treatment of cancers by
engaging the patient's own immune system against the tumor (1-3). Checkpoint pathways …

[HTML][HTML] Immune checkpoint inhibitors and immune-related adverse renal events

SM Herrmann, MA Perazella - Kidney international reports, 2020 - Elsevier
Renal toxicities have been increasingly recognized as complications of the immune
checkpoint inhibitors (ICIs). Recent studies have outlined the incidence and potential risk …

[HTML][HTML] Immune checkpoint inhibitor nephrotoxicity: what do we know and what should we do?

MA Perazella, AC Shirali - Kidney International, 2020 - Elsevier
Immune checkpoint inhibitors have dramatically improved cancer therapy for many patients.
These humanized monoclonal antibodies against various immune checkpoints (receptors …

Kidney biopsy should be performed to document the cause of immune checkpoint inhibitor–associated acute kidney injury: PRO

M Eijgelsheim, B Sprangers - Kidney360, 2020 - journals.lww.com
Immune checkpoint inhibitors (CPIs) have significantly improved the outcome for patients
with cancer by effectively overcoming cancer resistance by allowing the host immune system …

[HTML][HTML] Acute kidney injury associated with immune checkpoint inhibitor therapy: incidence, risk factors and outcomes

A Meraz-Muñoz, E Amir, P Ng… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICPi) are a novel and promising anti-cancer
therapy. There are limited data on the incidence, risk factors and outcomes of acute kidney …

Renal complications of immune checkpoint blockade

N Murakami, S Motwani, LV Riella - Current problems in cancer, 2017 - Elsevier
Immune checkpoint inhibitors have been approved for a variety of cancer species. Renal
complications in use of these agents are not very common compared with other immune …

[HTML][HTML] Nephrotoxicity of immune checkpoint inhibitors: acute kidney injury and beyond

M Tinawi, B Bastani - Cureus, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are novel humanized monoclonal antibodies that
release the brakes on the immune system, resulting in the destruction of tumor cells. ICIs are …

Renal effects of immune checkpoint inhibitors

H Izzedine, C Mateus, C Boutros… - Nephrology Dialysis …, 2017 - academic.oup.com
Recent advances in immune checkpoint inhibitor (ICPI) development have led to major
improvements in oncology patient outcomes. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) …