Although it has been well established that spermatogenic cells undergo apoptosis when
treated with ethanol, the molecular mechanisms behind it remain to be investigated. Adult …

Background: Chronic ethanol abuse causes testicular atrophy and male infertility in
alcoholic men. It is well known that ethanol exposure disrupts the hypothalamic‐pituitary …

The Fas system is involved in the regulation of germ cell apoptosis associated with testicular
injury in experimental animals exposed to various insults. We tested the hypothesis that …

Ethanol exposure is known to suppress male reproductive activity in laboratory animals and
humans. The present study was designed to evaluate whether chronic ethanol exposure …

Ethanol enhances apoptosis in testicular germ cells. Zinc reduces ethanol-induced
apoptosis of somatic cells through inhibition of caspase-mediated pathways. Little is known …

Objective Chronic ethanol abuse causes reproductive organ failure and infertility in both
humans and laboratory animals. Since sperm has a critical role in reproductive function, the …

The study was undertaken to evaluate the possible involvement of oxidative stress in the
pathogenesis of ethanol induced testicular atrophy in rats. Adult male rats were orally …

It was suggested that chronic ethanol exposure could result in testicular germ cell apoptosis,
but the mechanism is still unclear. In the present study, we use a model of transgenic mice …

Apoptosis is an important regulatory event in testicular homeostasis and optimization of
sperm production. Sertoli cells (SCs) form the blood–testis barrier creating a special …

The present study was conducted to provide biochemical and morphological evidence for
ethanol-induced impairment of testicular development. The specific activities of testicular …