Gingipain adhesin domains mediate Porphyromonas gingivalis adherence to epithelial cells

T Chen, MJ Duncan - Microbial pathogenesis, 2004 - Elsevier
Porphyromonas gingivalis, a Gram-negative oral anaerobe, interacts with epithelium lining
the gingival sulcus. Continuing our studies on the role of gingipain cysteine proteinases in P …

Characterization of Porphyromonas gingivalis-Induced Degradation of Epithelial Cell Junctional Complexes

J Katz, V Sambandam, JH Wu, SM Michalek… - Infection and …, 2000 - Am Soc Microbiol
Porphyromonas gingivalis is considered among the etiological agents of human adult
periodontitis. Although in vitro studies have shown that P. gingivalis has the ability to invade …

Synthetic peptides analogous to the fimbrillin sequence inhibit adherence of Porphyromonas gingivalis

JY Lee, HT Sojar, GS Bedi, RJ Genco - Infection and immunity, 1992 - Am Soc Microbiol
Fimbriae are important in the adherence of many bacterial species to the surfaces they
eventually colonize. Porphyromonas (Bacteroides) gingivalis fimbriae appear to mediate …

Molecular Interactions of Porphyromonas gingivalisFimbriae with Host Proteins: Kinetic Analyses Based on Surface Plasmon Resonance

A Amano, T Nakamura, S Kimura, I Morisaki… - Infection and …, 1999 - Am Soc Microbiol
Fimbriae of Porphyromonas gingivalis are thought to play an important role in the
colonization and invasion of periodontal tissues. In this study, we analyzed the interactions …

Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction

RT Evans, B Klausen, HT Sojar, GS Bedi… - Infection and …, 1992 - Am Soc Microbiol
Adhesive fimbriae from Porphyromonas gingivalis are cell surface structures which may be
important in the virulence of this oral pathogen and thus may serve as a critical or target …

Fimbria‐dependent activation of pro‐inflammatory molecules in Porphyromonas gingivalis infected human aortic endothelial cells

Y Takahashi, M Davey, H Yumoto… - Cellular …, 2006 - Wiley Online Library
Epidemiological studies support that chronic periodontal infections are associated with an
increased risk of cardiovascular disease. Previously, we reported that the periodontal …

Role for fimbriae and lysine-specific cysteine proteinase gingipain K in expression of interleukin-8 and monocyte chemoattractant protein in Porphyromonas gingivalis …

H Nassar, HH Chou, M Khlgatian… - Infection and …, 2002 - Am Soc Microbiol
Recent cross-sectional and prospective epidemiological studies have demonstrated an
association between periodontal disease and atherosclerosis and human coronary heart …

[HTML][HTML] TLR2 activation by porphyromonas gingivalis requires both PPAD activity and fimbriae

A Wielento, GP Bereta, KB Łagosz-Ćwik… - Frontiers in …, 2022 - frontiersin.org
Porphyromonas gingivalis, a keystone oral pathogen implicated in development and
progression of periodontitis, may also contribute to the pathogenicity of diseases such as …

Lipid raft‐dependent uptake, signalling and intracellular fate of Porphyromonas gingivalis in mouse macrophages

M Wang, G Hajishengallis - Cellular microbiology, 2008 - Wiley Online Library
Lipid rafts are cholesterol‐enriched microdomains involved in cellular trafficking and
implicated as portals for certain pathogens. We sought to determine whether the oral …

Interleukin‐34 permits Porphyromonas gingivalis survival and NF‐κB p65 inhibition in macrophages

A Almarghlani, RP Settem, AJ Croft… - Molecular oral …, 2022 - Wiley Online Library
Abstract Interleukin‐34 (IL‐34) is a cytokine that supports the viability and differentiation of
macrophages. An important cytokine for the development of epidermal immunity, IL‐34, is …