Periodontal disease is the major cause of adult tooth loss and is commonly characterized by
a chronic inflammation caused by infection of oral bacteria. Porphyromonas gingivalis (P …

Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Porphyromonas gingivalis, the major etiologic agent of chronic periodontitis, produces a
broad spectrum of virulence factors, including outer membrane vesicles. In this study, we …

The presence of Porphyromonas gingivalis in the periodontal pocket and the high levels of
gingipain activity detected in gingival crevicular fluid could implicate a role for gingipains in …

Coaggregation of Porphyromonas gingivalis and oral streptococci is thought to play an
important role in P. gingivalis colonization. Previously, we reported that P. gingivalis major …

Bacterial fimbriae are an important pathogenic factor. It has been demonstrated that fimbrial
protein encoded by fimA gene (FimA fimbriae) of Porphyromonas gingivalis not only …

Macrophages adapt both phenotypically and functionally to the cytokine balance in host
tissue microenvironments. Recent studies established that macrophages contribute an …

Porphyromonas gingivalis can induce its uptake by host epithelial cells; however, the nature
and role of the P. gingivalis molecules involved in this invasion process have yet to be …

Background Porphyromonas gingivalis inhibits oral epithelial wound healing in vitro more
strongly than other oral bacteria, but it is unknown why P. gingivalis is such a potent inhibitor …

Selected cell envelope components of Porphyromonas gingivalis were tested in a BALB/c
mouse model in an attempt to elucidate further the outer membrane components of this …