The study of human pulmonary immunity against Mycobacterium tuberculosis (M. tb)
provides a unique window into the biological interactions between the human host and M. tb …

Biomarkers for tuberculosis treatment outcome will assist in guiding individualized treatment
and evaluation of new therapies. To identify candidate biomarkers, RNA sequencing of …

Screening and Preventive Therapy for Tuberculosis - Clinics in Chest Medicine Skip to Main
Content Clinics in Chest Medicine Log in Register Log in Subscribe Claim Skip menu …

Targeted testing and treatment of individuals with latent tuberculosis infection at increased
risk of progression to active disease is a key element of tuberculosis control. This strategy is …

BACKGROUND. The identification and treatment of individuals with tuberculosis (TB) is a
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease …

Background Targeted preventive therapy for individuals at highest risk of incident
tuberculosis might impact the epidemic by interrupting transmission. We tested performance …

ABSTRACT A major impediment to tuberculosis (TB) vaccine development is the lack of
reliable correlates of immune protection or biomarkers that would predict vaccine efficacy …

One third of the world's population is infected with Mycobacterium tuberculosis (M. tb). A
vaccine that would prevent progression to TB disease will have a dramatic impact on the …

Background Mycobacterium tuberculosis infection is a leading cause of infectious death
worldwide. Gene-expression microarray studies profiling the blood transcriptional response …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) latently infects
approximately one-fourth of the world's population. The immune mechanisms that govern …