Philip M Hopkins sarcolemma. Without the ClÀ current to maintain resting membrane
potential, the muscle would not repolarize sufficiently to regenerate the active state of the …

Neuromuscular transmission at the skeletal muscle occurs when a quantum of acetylcholine
from the nerve ending is released and binds to the nicotinic acetylcholine receptors on the …

IMPLICATIONS: Voltage-gated sodium channels mediate the initiation and propagation of
action potentials along the sarcolemma. Results from our study show that those channels …

The neuromuscular junction (NMJ) is structured and powered to transduce electrical activity
from the distal nerve terminal of a motor neurone via the neuromuscular cleft to the post …

The cardiac cells (myocytes) are branched filament-like structures 10-20 µm in diameter and
50-100 µm long. Approximately every 2 µm in their longitudinal axis, transverse (T) tubules …

The term “excitation–contraction (EC) coupling” was introduced by Alexander Sandow
(Sandow, 1952) as “the entire sequence of reactions—excitation, inward acting link, and …

Neuromuscular transmission has been investigated vigorously for more than a century and
more is known about it than about any other synaptic function. Yet, our understanding is still …

Background Although the respiratory muscles (the diaphragm and the laryngeal adductors)
recover from paralysis more rapidly than does the adductor pollicis, patients can develop …

Pharmacology of Neuromuscular Function, Second Edition provides information pertinent to
drugs that affect membrane potentials of the conduction of action potentials in nerve endings …

SUMMARY 1 Excitation–contraction coupling is broadly defined as the process linking the
action potential to contraction in striated muscle or, more narrowly, as the process coupling …