Transcriptional Regulation of Agouti-Related Protein (Agrp) in Transgenic Mice

CB Kaelin, AW Xu, XY Lu, GS Barsh - Endocrinology, 2004 - academic.oup.com
Agouti-related protein (Agrp) encodes a hypothalamic neuropeptide that promotes positive
energy balance by stimulating food intake and reducing energy expenditure. Agrp …

[HTML][HTML] Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

H Makimura, TM Mizuno, JW Mastaitis, R Agami… - BMC neuroscience, 2002 - Springer
Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP)
plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no …

Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger …

CB Kaelin, L Gong, AW Xu, F Yao… - Molecular …, 2006 - academic.oup.com
Energy homeostasis depends on the regulation of hypothalamic neurons by leptin, an
adipocyte hormone whose circulating levels communicate body energy stores. Leptin …

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

S Qian, H Chen, D Weingarth… - … and cellular biology, 2002 - Am Soc Microbiol
Abstract Agouti-related protein (AgRP), a neuropeptide abundantly expressed in the arcuate
nucleus of the hypothalamus, potently stimulates feeding and body weight gain in rodents …

The role of the Agouti-Related Protein in energy balance regulation

O Ilnytska, G Argyropoulos - Cellular and molecular life sciences, 2008 - Springer
The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food
intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency …

[HTML][HTML] Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish

I Shainer, A Buchshtab, TA Hawkins, SW Wilson… - Scientific Reports, 2017 - nature.com
The neuropeptide agouti-related protein (AgRP) is expressed in the arcuate nucleus of the
mammalian hypothalamus and plays a key role in regulating food consumption and energy …

The Agouti-related protein and its role in energy homeostasis

AM Stütz, CD Morrison, G Argyropoulos - Peptides, 2005 - Elsevier
The melanocortin system plays an important role in the regulation of energy homeostasis.
The Agouti-related protein (AGRP) is a natural antagonist of the action of alpha-melanocyte …

AgRP neuron-specific deletion of glucocorticoid receptor leads to increased energy expenditure and decreased body weight in female mice on a high-fat diet

M Shibata, R Banno, M Sugiyama, T Tominaga… - …, 2016 - academic.oup.com
Agouti-related protein (AgRP) expressed in the arcuate nucleus is a potent orexigenic
neuropeptide, which increases food intake and reduces energy expenditure resulting in …

Control elements in the neighboring ATPase gene influence spatiotemporal expression of the human agouti-related protein

O Ilnytska, MA Sözen, R Dauterive… - Journal of molecular …, 2009 - Elsevier
The agouti-related protein (AgRP) is an orexigenic peptide that plays a significant role in the
regulation of energy balance. It is expressed in the hypothalamus, the adrenal glands, and …

[HTML][HTML] Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

MJ Krashes, S Koda, CP Ye, SC Rogan… - The Journal of …, 2011 - Am Soc Clin Investig
Several different neuronal populations are involved in regulating energy homeostasis.
Among these, agouti-related protein (AgRP) neurons are thought to promote feeding and …