Microsatellite instability (MSI) in tumors from patients with hereditary non‐polyposis
colorectal cancer (HNPCC) is caused by germline mutations in mismatch repair (MMR) …

Human gastric carcinoma shows a higher prevalence of microsatellite instability (MSI) than
does any other type of sporadic human cancer. The reasons for this high frequency of MSI …

Mutation of DNA mismatch repair genes has rarely been documented in sporadic gastric
carcinoma with microsatellite instability (MSI). In sporadic colorectal carcinoma, hMLH1 …

Microsatellite instability (MSI), which is recognized as an important mechanism in
tumorigenesis, has been reported in familial gastric cancers (FGC). However, genetic …

Recent studies have demonstrated the presence of microsatellite instability (MSI) in tumors
from patients with hereditary nonpolyposis colon cancer and in a subset of patients with …

In hereditary nonpolyposis colorectal cancer (HNPCC), patients' mismatch repair (MMR)
gene mutations cause MMR deficiency, leading to microsatellite instability (MSI-H). MSI-H is …

Microsatellite instability (MSI) is a hallmark of hereditary nonpolyposis colorectal cancer, and
in these patients, results from inherited defects in DNA mismatch repair genes, mostly MSH2 …

A significant portion of gastric cancers exhibit defective DNA mismatch repair, manifested as
microsatellite instability (MSI). High-frequency MSI (MSI-H) is associated with …

Aberrant 5′ CpG island methylation is an alternative mechanism of gene inactivation
during the development of cancer as demonstrated for several tumor‐suppressor genes …

AIM: To appraise the correlation of mutation and methylation of hMSH1 with microsatellite
instability (MSI) in gastric cancers. METHODS: Mutation of hMLH1 was detected by Two …