[HTML][HTML] Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis …

WZ Zhong, HH Yan, KN Chen, C Chen… - Signal transduction and …, 2023 - nature.com
EMERGING-CTONG 1103 showed improved progression-free survival (PFS) with
neoadjuvant erlotinib vs. chemotherapy for patients harbouring EGFR sensibility mutations …

CTONG1103: Final overall survival analysis of the randomized phase 2 trial of erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 …

YL Wu, W Zhong, KN Chen, C Chen, F Yang, XN Yang… - 2021 - ascopubs.org
8502 Background: Median Overall survival (mOS) of stage IIIA resected NSCLC was 59.4
months (m) in CTONG 1104 adj gefitinib and 26.2 m in SAKK neoadjuvant chemo trial …

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE To assess the benefits of epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors as neoadjuvant/adjuvant therapies in locally advanced EGFR mutation …

CTONG 1103: Erlotinib versus gemcitabine plus cisplatin as neo-adjuvant treatment for stage IIIA-N2 EGFR-mutation non-small cell lung cancer (EMERGING): a …

WZ Zhong, YL Wu, KN Chen, C Chen… - Annals of …, 2018 - annalsofoncology.org
Background: Cisplatin-based doublet chemotherapy as neoadjuvant treatment for IIIA-N2
non-small cell lung cancer (NSCLC) give patients 5% survival benefit. EGFR-TKIs have …

Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation‐Positive Non‐Small Cell Lung Cancer: A Prospective, Single‐Arm, Phase II Study

L Xiong, R Li, J Sun, Y Lou, W Zhang, H Bai… - The …, 2019 - academic.oup.com
Abstract Lessons Learned The findings of this prospective, single‐arm, phase II study
showed that neoadjuvant erlotinib was well tolerated and might improve the radical …

[HTML][HTML] Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation …

W Zhong, X Yang, H Yan, X Zhang, J Su… - Journal of Hematology & …, 2015 - Springer
Background Neoadjuvant erlotinib and customized adjuvant therapy are appealing but
controversial. The purpose of this study was to evaluate the role of biomarker-guided …

[HTML][HTML] Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

H Zhai, W Zhong, X Yang, YL Wu - Translational lung cancer …, 2015 - ncbi.nlm.nih.gov
Abstract The Lung Adjuvant Cisplatin Evaluation (LACE) meta-analysis and the meta-
analysis of individual participant data reported by non-small cell lung cancer (NSCLC) Meta …

Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients

L Xiong, Y Lou, H Bai, R Li, J Xia… - Journal of …, 2020 - journals.sagepub.com
Background The optimal neoadjuvant regimen for locally advanced resectable non-small
cell lung cancer (NSCLC) remains controversial. EGFR inhibitors have significantly …

[HTML][HTML] Adjuvant EGFR TKI therapy for resectable non-small cell lung cancer: new era for personalized medicine

P Shen, W Zhong - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
Whether the success of EGFR TKIs in the advanced setting could transfer to adjuvant setting
for patients with early-stage disease attracts much more attention. The use of EGFR TKI …

CTONG1104: Adjuvant gefitinib versus chemotherapy for resected N1-N2 NSCLC with EGFR mutation—Final overall survival analysis of the randomized phase III trial …

YL Wu, W Zhong, Q Wang, W Mao, ST Xu, L Wu… - 2020 - ascopubs.org
9005 Background: ADJUVANT-CTONG1104, a randomized phase 3 trial showed adjuvant
gefitinib treatment significantly improved disease-free survival (DFS) vs standard doublet …