Effects of chronic intranasal oxytocin on behavior and cerebral glucose uptake in juvenile titi monkeys

RA Del Razo, T Berger, AJ Conley, SM Freeman… - …, 2020 - Elsevier
Intranasal oxytocin (IN OXT) has been proposed as a treatment for autism spectrum disorder
(ASD); however, little is known about the effects of long-term exposure. This is the first study …

[HTML][HTML] Long term effects of chronic intranasal oxytocin on adult pair bonding behavior and brain glucose uptake in titi monkeys (Plecturocebus cupreus)

R Arias-del Razo, MLV Vazquez, P Turcanu… - Hormones and …, 2022 - Elsevier
Intranasal oxytocin (IN OXT) administration has been proposed as a pharmacological
treatment for a range of biomedical conditions including neurodevelopmental disorders …

[HTML][HTML] Long-term exposure to intranasal oxytocin in a mouse autism model

KL Bales, M Solomon, S Jacob, JN Crawley… - Translational …, 2014 - nature.com
Oxytocin (OT) is a neuropeptide involved in mammalian social behavior. It is currently in
clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy …

Aerosolized oxytocin increases cerebrospinal fluid oxytocin in rhesus macaques

ME Modi, F Connor-Stroud, R Landgraf… - …, 2014 - Elsevier
Intranasal (IN) administration is a widely used method for examining the effect of oxytocin
(OT) on social behavior and cognition in healthy subjects and psychiatric populations. IN-OT …

[HTML][HTML] Intranasal oxytocin failed to affect chimpanzee (Pan troglodytes) social behavior

D Proctor, SE Calcutt, K Burke… - Animal behavior and …, 2016 - ncbi.nlm.nih.gov
Oxytocin has been suggested as a treatment to promote positive social interactions in
people with Autism Spectrum Disorders (ASD). However, it is difficult to test this effect …

Effects of chronic oxytocin on attention to dynamic facial expressions in infant macaques

LA Parr, JM Brooks, T Jonesteller, S Moss… - …, 2016 - Elsevier
Studies in a variety of species have reported enhanced prosocial effects after an acute
administration of the neuromodulating hormone, oxytocin (OT). Although the exact …

[HTML][HTML] Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial

E Anagnostou, L Soorya, W Chaplin, J Bartz… - Molecular autism, 2012 - Springer
Background There are no effective medications for the treatment of social cognition/function
deficits in autism spectrum disorder (ASD), and adult intervention literature in this area is …

Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

KJ Parker, O Oztan, RA Libove… - Proceedings of the …, 2017 - National Acad Sciences
Autism spectrum disorder (ASD) is characterized by core social deficits. Prognosis is poor, in
part, because existing medications target only associated ASD features. Emerging evidence …

Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions

LA Parr, M Modi, E Siebert, LJ Young - Psychoneuroendocrinology, 2013 - Elsevier
Intranasal oxytocin (IN-OT) modulates social perception and cognition in humans and could
be an effective pharmacotherapy for treating social impairments associated with …

Intranasal oxytocin in the treatment of autism spectrum disorders: a review of literature and early safety and efficacy data in youth

E Anagnostou, L Soorya, J Brian, A Dupuis, D Mankad… - Brain research, 2014 - Elsevier
Background There is a paucity of treatments targeting core symptom domains in Autism
Spectrum Disorder (ASD). Several animal models and research in typically developing …