Aims To examine a novel strategy to enhance the survival of grafted neural stem cells (NSC
s) in stroke model. Methods Using a cell counting kit‐8 (CCK‐8) and TUNEL assay to test …

Objective: Although cerebral ischemia can activate endogenous reparative processes, such
as proliferation of endogenous neural stem cells (NSCs) in the subventricular zone (SVZ) …

Promoting regenerative repair, including neurogenesis and angiogenesis, may provide a
new therapeutic strategy for treatment of stroke. P53, a well-documented transcription factor …

Neural progenitor cell (NPC) transplantation has been shown to be beneficial in the
ischemic brain. However, the low survival rate of transplanted NPCs in an ischemic …

Cerebrovascular disease such as stroke is one of the most common diseases in the aging
population, and neural stem cells (NSCs) transplantation may provide an alternative therapy …

Objective Although platelet-derived growth factor receptor (PDGFR)-β mediates the self-
renewal and multipotency of neural stem/progenitor cells (NSPCs) in vitro and in vivo, its …

Hypoxia conditioning could increase the survival of transplanted neuronal progenitor cells
(NPCs) in rats with cerebral ischemia but could also hinder neuronal differentiation partly by …

Previous studies indicated the beneficial effects of glial cell line-derived neurotrophic factor
(GDNF) and transplanted neural stem cells (NSCs) on stroke. Here, we explored whether …

Background Our previous studies have indicated that the beneficial effects of grafting neural
stem cells (NSCs) overexpressing glial cell line-derived neurotrophic factor (GDNF) in rats …

Neural progenitor cells (NPCs) therapy offers great promise in hypoxic-ischemic (HI) brain
injury. However, the poor survival of implanted NPCs in the HI host environment limits their …