Aging impairs immunity to promote diseases, especially respiratory viral infections. The
current COVID-19 pandemic, resulting from SARS-CoV-2, induces acute pneumonia, a …

Older adults are far more vulnerable to adverse health outcomes and mortality after
contracting COVID-19. There are likely multiple age-related biological, clinical, and …

Bearing a strong resemblance to the phenotypic and functional remodeling of the immune
system that occurs during aging (termed immunesenescence), the immune response to …

Aging is characterized by the dynamic remodeling of the immune system designated
“immunosenescence,” and is associated with altered hematopoiesis, thymic involution, and …

Covid-19 and Immunity in Aging Populations As billions of dollars flow into research and
development efforts aimed at controlling SARS-CoV-2, the pandemic response remains …

The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …

The process of aging is accompanied by a dynamic restructuring of the immune response, a
phenomenon known as immunosenescence. This mini-review navigates through the …

SARS‐CoV‐2 is a novel betacoronavirus which infects the lower respiratory tract and can
cause coronavirus disease 2019 (COVID‐19), a complex respiratory distress syndrome …

There is a great deal of debate on the question of whether or not we know what ageing is
(Ref. Cohen et al., 2020). Here, we consider what we believe to be the especially confused …

Morbidity and mortality in response to SARS-CoV-2 infection are significantly elevated in
people of advanced age. To understand the underlying biology of this phenotype, we utilize …