Elderly at time of COronaVIrus disease 2019 (COVID-19): possible role of immunosenescence and malnutrition

L Bencivenga, G Rengo, G Varricchi - Geroscience, 2020 - Springer
The unprecedented COVID-19 pandemic is rapidly and unpredictably evolving and the
majority of deaths are occurring in older people. A partial description of the magnitude of the …

The lethal sex gap: COVID-19

EJ Márquez, J Trowbridge, GA Kuchel, J Banchereau… - Immunity & …, 2020 - Springer
Abstract While Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is disrupting lives across the globe for everyone, it …

[PDF][PDF] Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity

CR Moderbacher, SI Ramirez, JM Dan, A Grifoni… - Cell, 2020 - cell.com
Limited knowledge is available on the relationship between antigen-specific immune
responses and COVID-19 disease severity. We completed a combined examination of all …

Geriatric population during the COVID-19 pandemic: problems, considerations, exigencies, and beyond

K Dhama, SK Patel, R Kumar, J Rana… - Frontiers in public …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more
than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020 …

COVID-19 in the elderly people and advances in vaccination approaches

K Dhama, SK Patel, S Natesan, KS Vora… - Human vaccines & …, 2020 - Taylor & Francis
The rapid worldwide spread of the COVID-19 pandemic, caused by the newly emerged
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in tens of …

SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

J Nikolich-Zugich, KS Knox, CT Rios, B Natt… - Geroscience, 2020 - Springer
Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

[HTML][HTML] COVID-19, virology and geroscience: a perspective

C Vellas, P Delobel, PDS Barreto, J Izopet - The journal of nutrition, health …, 2020 - Elsevier
A new coronavirus, called SARS-CoV-2, was identified in Wuhan, China, in December 2019.
The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease …

[HTML][HTML] Covid-19 pandemic: maximizing future vaccination treatments considering aging and frailty

S Palermo - Frontiers in medicine, 2020 - frontiersin.org
The COVID-19 pandemic is proving to be a multiplier of inequalities. Especially toward the
elderly population. A voiceless scream that comes from geriatrics, nursing homes, hospices …

Why the elderly appear to be more severely affected by COVID‐19: the potential role of immunosenescence and CMV

S Kadambari, P Klenerman… - Reviews in medical …, 2020 - Wiley Online Library
The significantly higher mortality rates seen in the elderly compared with young children
during the coronavirus disease 2019 (Covid‐19) pandemic is likely to be driven in part by an …

The role of immune activation and antigen persistence in acute and long COVID

S Opsteen, JK Files, T Fram… - Journal of Investigative …, 2023 - journals.sagepub.com
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) triggered the
global coronavirus disease 2019 (COVID-19) pandemic. Although most infections cause a …