PURPOSE: Many occupational factors can cause asthma or reactivate preexisting disease.
We carried out a critical review and synthesis of the available literature to estimate the …

Workplace exposures trigger or aggravate asthma principally by three links:(1) immunologic
or allergic sensitization to a substance;(2) acute exposure to a high concentration of an …

Only a few threshold limit values exist at present for allergens in the workplace known to
cause bronchial asthma. This contrasts with the great number of occupational asthma cases …

A retrospective investigation of 86 asthmatic subjects defined clinical features of irritant-
induced asthma and assessed the contributory role of an allergic predisposition. Three …

Several studies on the prognosis of occupational asthma have shown that a significant
proportion of patients continue to experience asthmatic symptoms and nonspecific bronchial …

The term irritant‐induced (occupational) asthma (IIA) has been used to denote various
clinical forms of asthma related to irritant exposure at work. The causal relationship between …

Certain chemicals are known to cause occupational respiratory allergy associated with
symptoms of pulmonary distress, including asthma and rhinitis. While there is no doubt that …

Occupational immunologic lung disease can be identified both in the individual patient
under laboratory conditions and in a population of workers in industry. Occupational airways …

The relationships among bronchial responsiveness to allergen, bronchial responsiveness to
histamine, and cutaneous sensitivity to allergen were examined in 25 asthmatic subjects …

Allergen inhalation challenge has been useful for examining the mechanisms of allergen-
induced airway inflammation and the associated physiological changes and for …