The vast majority of cancer-related deaths are attributable to metastasis. Effective treatment
of metastatic disease will be improved by a better understanding of the molecular …

The multizinc finger containing transcription factor ZEB1 plays crucial roles during various
aspects of mammalian development and tumorigenesis. Best studied in human tumors …

Zinc finger E-box binding homeobox factor 1 (ZEB1), as a crucial mediator of “epithelial-
mesenchymal transition,” contributes to malignant progression of various epithelial tumors …

Zinc finger E-box binding homeobox 1 (ZEB1) is an important transcription factor in epithelial
mesenchymal transition (EMT) which participates in the numerous life processes, such as …

Glioblastoma remains one of the most lethal types of cancer, and is the most common brain
tumour in adults. In particular, tumour recurrence after surgical resection and radiation …

ZEB2 is a key factor in epithelial-mesenchymal transition (EMT), a program controlling cell
migration in embryonic development and adult tissue homeostasis. We demonstrated a role …

Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by an aggressive
biology and poor prognosis. Experimental evidence has suggested a role for the …

Epithelial-mesenchymal transition (EMT) is a process implicated in tumor invasion and
metastasis. During EMT, epithelial cells undergo molecular changes to acquire …

Cancer metastasis remains a significant challenge and the leading cause of cancer-
associated deaths. It is postulated that during metastasis cells undergo epithelial-to …

Epithelial-to-mesenchymal transition (EMT)-inducing transcription factors (TF) are well
known for their ability to induce mesenchymal states associated with increased migratory …