Comparison of time-resolved and-unresolved measurements of deoxyhemoglobin in brain.

B Chance, JS Leigh, H Miyake… - Proceedings of the …, 1988 - National Acad Sciences
Continuous (CW) and pulsed light were used for the noninvasive measurement of
hemoglobin oxygenation in tissues. A dual wavelength method of continuous illumination …

Time-dependent optical spectroscopy and imaging for biomedical applications

BC Wilson, EM Sevick, MS Patterson… - Proceedings of the …, 1992 - ieeexplore.ieee.org
The application of optical spectroscopy and imaging in living tissue is complicated by
multiple scattering of light. In spectroscopy, this scattering causes uncertainty in the …

Effects of solutes on optical properties of biological materials: models, cells, and tissues

B Chance, HL Liu, T Kitai, YT Zhang - Analytical biochemistry, 1995 - Elsevier
Perturbations of scattering background for absorbance measurements by photon diffusion
techniques complicate algorithms used for determining the concentration of blood and the …

Development of time-resolved spectroscopy system for quantitative noninvasive tissue measurement

M Miwa, Y Ueda, B Chance - Optical Tomography, Photon …, 1995 - spiedigitallibrary.org
Near IR time resolved spectroscopy has been studied for quantitative determination of
absorbance in highly scattering medium such as tissue. When a very narrow optical pulse is …

Measurement of the optical properties of the skull in the wavelength range 650-950 nm

M Firbank, M Hiraoka, M Essenpreis… - Physics in Medicine & …, 1993 - iopscience.iop.org
The optical properties of samples of bone from pig skull have been measured over the
wavelength range 650-950 nm. The scattering phase function was measured on thin …

Data analysis methods for near-infrared spectroscopy of tissue: problems in determining the relative cytochrome aa3 concentration

M Cope, P van der Zee, M Essenpreis… - … and Imaging of …, 1991 - spiedigitallibrary.org
In the brain of the adult rat, the ratio of the absorption coefficient of hemoglobin to that of the
cytochromes is approximately ten and in the newborn rat brain the ratio is even higher …

The Effects of ex vivo Handling Procedures on the Near‐Infrared Raman Spectra of Normal Mammalian Tissues

MG Shim, BC Wilson - Photochemistry and photobiology, 1996 - Wiley Online Library
Recent studies in the literature have investigated the feasibility of tissue diagnostics based
on Raman spectroscopy. The majority of these compare the ex vivo spectra of normal and …

An investigation of factors affecting the accuracy of in vivo measurements of skin pigments by reflectance spectrophotometry

M Hajizadeh-Saffar, JW Feather… - Physics in Medicine & …, 1990 - iopscience.iop.org
Factors affecting the accuracy of the in vivo measurement of cutaneous pigments and blood
oxygenation by reflectance spectrophotometry have been examined. It was found that stray …