Introduction Although major changes of the immune system have been described in sepsis,
it has never been studied whether these may differ in relation to the type of underlying …

Introduction Hospital-acquired pneumonia after surgery is one of the major causes of septic
shock. The excessive inflammatory response appears to be responsible for the increased …

Introduction Severe sepsis is characterized by an initial hyper-inflammatory response that
may progress to an immune-suppressed state associated with increased susceptibility to …

Background Sepsis is a leading cause of mortality and critical illness worldwide and is
associated with an increased mortality rate in the months following hospital discharge. The …

Introduction Our aim was to define early changes of lymphocytes and of NK cells in severe
sepsis and to correlate them with serum levels of soluble triggering receptor expressed on …

Introduction Host immunity should play a principal role in determining both the outcome and
recovery of patients with sepsis that originated from a microbial infection. Quantification of …

Purpose The histopathology of sepsis-associated acute kidney injury (AKI) in critically ill
patients remains an understudied area. Previous studies have identified that acute tubular …

Introduction Given the pivotal role of T lymphocytes in the immune system, patients with
septic shock may show T cell abnormalities. We have characterised the T cell compartment …

Introduction It has recently been proposed that B lymphocytes are involved in sepsis
pathogenesis. The goal of this study is to investigate potential abnormalities in a subset …

Background Although the immune function of neutrophils in sepsis has been well described,
the heterogeneity of neutrophils remains unclear during the process of sepsis. Methods In …