5α-reductase activity. The exact mechanism by which OCs reduce androgen production by
the adrenal glands is not known, though it has been demonstrated with radioimmune …

Androgenic disorders of female skin such as hirsutism, acne and alopecia are etiologically
caused by androgen excess. Skin 5α-reductase activity is a major factor influencing the …

Abstract Skin 5 [alpha]-reductase activity is the major factor influencing the manifestation of
androgen excess. Although oral contraceptives have been useful for the treatment of …

Oral contraceptives (OC) suppress excess androgen production; however, different
progestins in combination with low-dose estrogens produce divergent effects on sex …

Although acne is seldom associated with high serum levels of androgens, it has been shown
that female acne patients have definite increases in ovarian and adrenal androgen levels …

Oral contraceptives (OCs) can reduce acne by lowering the production of adrenal and
ovarian androgens, by inhibiting 5-alpha-reductase, which in turn, reduces the levels of …

Background Dihydrotestosterone mediates androgen-dependent diseases, such as acne,
hirsutism, and androgenetic alopecia. This hormone is produced from testosterone by the 5α …

Hormones and Acne—Acne can reflect multiple etiologies, including such contributing
factors as infection, abnormal keratinization, immunologic reaction, and hormonal …

Acne is caused by the action of dihydrotestosterone, derived from endogenous and
exogenous precursors, likely acting synergistically with insulin-like growth factor-1. These …

Cutaneous manifestations of hyperandrogenic disorders (acne, seborrhea, hirsutism and
androgenetic alopecia) can be caused by elevated levels of free testosterone or androgen …