Integrating biological knowledge into variable selection: an empirical Bayes approach with an application in cancer biology

SM Hill, RM Neve, N Bayani, WL Kuo, S Ziyad… - BMC …, 2012 - Springer
Background An important question in the analysis of biochemical data is that of identifying
subsets of molecular variables that may jointly influence a biological response. Statistical …

[HTML][HTML] A selective review of group selection in high-dimensional models

J Huang, P Breheny, S Ma - Statistical science: a review journal of …, 2012 - ncbi.nlm.nih.gov
Grouping structures arise naturally in many statistical modeling problems. Several methods
have been proposed for variable selection that respect grouping structure in variables …

Toward integrative Bayesian analysis in molecular biology

K Ickstadt, M Schäfer, M Zucknick - Annual Review of Statistics …, 2018 - annualreviews.org
In the postgenome era, multiple types of molecular data for the same set of samples are
often available and should be analyzed jointly in an integrative analysis in order to maximize …

Survival prediction and variable selection with simultaneous shrinkage and grouping priors

KH Lee, S Chakraborty, J Sun - Statistical Analysis and Data …, 2015 - Wiley Online Library
The presented work is motivated by the need of reliably estimating and predicting the
survival rates for individuals diagnosed with cancer, when gene expression profiles are …

Bayesian joint selection of genes and pathways: Applications in multiple myeloma genomics

L Zhang, JS Morris, J Zhang, RZ Orlowski… - Cancer …, 2014 - journals.sagepub.com
It is well-established that the development of a disease, especially cancer, is a complex
process that results from the joint effects of multiple genes involved in various molecular …

A variable selection approach for highly correlated predictors in high-dimensional genomic data

W Zhu, C Lévy-Leduc, N Ternès - Bioinformatics, 2021 - academic.oup.com
Motivation In genomic studies, identifying biomarkers associated with a variable of interest is
a major concern in biomedical research. Regularized approaches are classically used to …

Spike and slab gene selection for multigroup microarray data

H Ishwaran, JS Rao - Journal of the American Statistical …, 2005 - Taylor & Francis
DNA microarrays can provide insight into genetic changes that characterize different stages
of a disease process. Accurate identification of these changes has significant therapeutic …

Weighted lasso with data integration

LC Bergersen, IK Glad, H Lyng - Statistical applications in genetics …, 2011 - degruyter.com
The lasso is one of the most commonly used methods for high-dimensional regression, but
can be unstable and lacks satisfactory asymptotic properties for variable selection. We …

Within group variable selection through the exclusive lasso

F Campbell, GI Allen - 2017 - projecteuclid.org
Many data sets consist of variables with an inherent group structure. The problem of group
selection has been well studied, but in this paper, we seek to do the opposite: our goal is to …

Bayesian ranking and selection methods using hierarchical mixture models in microarray studies

H Noma, S Matsui, T Omori, T Sato - Biostatistics, 2010 - academic.oup.com
The main purpose of microarray studies is screening to identify differentially expressed
genes as candidates for further investigation. Because of limited resources in this stage …