Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies

SL Archer, EK Weir, MR Wilkins - Circulation, 2010 - Am Heart Assoc
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …

Pulmonary arterial hypertension–progress in understanding the disease and prioritizing strategies for drug development

P Ghataorhe, CJ Rhodes, L Harbaum… - Journal of Internal …, 2017 - Wiley Online Library
Pulmonary arterial hypertension (PAH), at one time a largely overlooked disease, is now the
subject of intense study in many academic and biotech groups. The availability of new …

[HTML][HTML] Pulmonary arterial hypertension management in asia: state of the art from Japan, and next steps

E Fung - JACC: Asia, 2022 - jacc.org
Pulmonary arterial hypertension (PAH) is a relatively rare disease and comprises a group of
progressive vascular disorders that may result in functional debilitation, cardiopulmonary …

Novel experimental therapies for treatment of pulmonary arterial hypertension

R Zolty - Journal of Experimental Pharmacology, 2021 - Taylor & Francis
Pulmonary arterial hypertension (PAH) is a progressive and devastating disease
characterized by pulmonary artery vasoconstriction and vascular remodeling leading to …

New drugs and therapies in pulmonary arterial hypertension

AJ Shah, T Beckmann, M Vorla, DK Kalra - International Journal of …, 2023 - mdpi.com
Pulmonary arterial hypertension is a chronic, progressive disorder of the pulmonary
vasculature with associated pulmonary and cardiac remodeling. PAH was a uniformly fatal …

Molecular genetic framework underlying pulmonary arterial hypertension

L Southgate, RD Machado, S Gräf… - Nature Reviews …, 2020 - nature.com
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …

Pulmonary hypertension care centers

M Chakinala, M McGoon - Advances in Pulmonary …, 2014 - meridian.allenpress.com
Our understanding and management of pulmonary arterial hypertension (PAH) has
advanced tremendously over the last 30 years. Numerous scientific discoveries have helped …

Pulmonary arterial hypertension: diagnosis, treatment, and novel advances

BA Maron, SH Abman, CG Elliott, RP Frantz… - American journal of …, 2021 - atsjournals.org
The diagnosis and management of pulmonary arterial hypertension (PAH) includes several
advances, such as a broader recognition of extrapulmonary vascular organ system …

An expanding role of biomarkers in pulmonary arterial hypertension

M Yildiz, A Sahin, M Behnes… - Current Pharmaceutical …, 2017 - ingentaconnect.com
Background: Pulmonary Arterial Hypertension (PAH) is a chronic disease which may cause
or result from multiple cardiopulmonary disorders. The disease has complex …

A review of pulmonary arterial hypertension: Part 1. Novel insights and classification

CT Gan, AV Noordegraaf, KMJ Marques… - Netherlands Heart …, 2004 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a disease characterised by an increased
pulmonary artery pressure. The precapillary pulmonary arteries show distinct …