Background This study aimed to conduct a systematic review and meta-analysis on
cognitive performances of patients with treatment-resistant schizophrenia (TRS) after …

Background: The aim of this study was to evaluate the 24-month response to clozapine in
patients with schizophrenia, schizoaffective disorder, or psychotic bipolar disorder. Method …

Background: Treatment-resistant schizophrenia is prevalent and difficult to manage, as
patients fail multiple antipsychotic trials before being considered as treatment-resistant …

Background Clozapine is uniquely effective in the management of treatment-resistant
schizophrenia (TRS). However, a substantial proportion of patients discontinue treatment …

Objective Early treatment of schizophrenia improves outcomes. Clozapine appears to have
unique benefit when other antipsychotic medication has failed. This systematic review and …

This study aims at identifying potential predictors of clinical response and functional
outcome in 101 neuroleptic-refractory patients with a DSM-III-R diagnosis of schizophrenia …

Background: We sought to identify baseline predictors of response to clozapine. Methods:
Data were from a 15-site randomized clinical trial comparing clozapine and haloperidol in …

Background: The treatment of schizophrenic patients who fail to respond to adequate trials
of neuroleptic drugs is a major challenge. Clozapine has been one treatment option; …

Randomized clinical trials have limitations because they focus on small samples of highly
selected patients. Observational studies, which follow large cohorts of typical patients …

Aims Few studies have investigated the prescription patterns of clozapine in outpatients with
schizophrenia in China. It is an important issue due to clozapine's high efficacy and …