Selective loss of estrogen receptor β in malignant human colon

EF Foley, AA Jazaeri, MA Shupnik, O Jazaeri, LW Rice - Cancer Research, 2000 - AACR
Epidemiological data suggest a protective effect for estrogen replacement therapy on colon
cancer. The estrogen receptor (ER) is required for the action of estrogen. The ER-β isoform …

Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer

M Campbell-Thompson, IJ Lynch, B Bhardwaj - Cancer research, 2001 - AACR
Colon cancer incidence and mortality rates are lower in females compared with males, and
numerous epidemiological studies suggest that estrogen replacement therapy (ERT) …

Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation

PA Konstantinopoulos, A Kominea, G Vandoros… - European journal of …, 2003 - Elsevier
Oestrogen Receptor β (ERβ) may protect against prostate and mammary cell proliferation
and malignant transformation. Epidemiological studies indicate that oestrogens may reduce …

Estrogen receptor β mRNA in colon cancer cells: growth effects of estrogen and genistein

N Arai, A Ström, JJ Rafter, JÅ Gustafsson - Biochemical and biophysical …, 2000 - Elsevier
Knowledge regarding the expression of the recently cloned estrogen receptor β (ERβ) in
colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell …

Loss of expression of oestrogen receptor β in colon cancer and its association with Dukes' staging

N Jassam, SM Bell, V Speirs… - Oncology …, 2005 - spandidos-publications.com
Gender differences in the incidence and behaviour of colon cancer suggest a hormonal
influence and epidemiological data suggest a protective effect for hormone replacement …

Estrogen receptor β is expressed in human colorectal adenocarcinoma

D Witte, M Chirala, A Younes, Y Li, M Younes - Human pathology, 2001 - Elsevier
Estrogen receptor β (ER-β) has recently been detected in a human colon cancer cell line.
The aim of this work was to determine whether ER-β is expressed in human colorectal …

Sex-specific differences in the expression levels of estrogen receptor subtypes in colorectal cancer

NC Nüssler, K Reinbacher, N Shanny, A Schirmeier… - Gender medicine, 2008 - Elsevier
Background: Altered expression of estrogen receptors alpha and beta (ERα and ERβ) has
been hypothesized to play a role in carcinogenesis. However, little is known about the sex …

[HTML][HTML] ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components

V Martineti, L Picariello, I Tognarini… - Endocrine-related …, 2005 - erc.bioscientifica.com
Several strands of evidence indicate that oestrogens exert a protective role against the
development of colon cancer through indirect and direct effects on colonic epithelium …

Reciprocal expression of ERα and ERβ is associated with estrogen-mediated modulation of intestinal tumorigenesis

MJ Weyant, AM Carothers, NN Mahmoud, HL Bradlow… - Cancer Research, 2001 - AACR
Menopausal hormone replacement therapy has been widely used to alleviate the symptoms
of menopause and to decrease the detrimental effects of ovarian hormone loss on bone …

Functional estrogen receptor β in colon cancer cells

G Fiorelli, L Picariello, V Martineti, F Tonelli… - Biochemical and …, 1999 - Elsevier
Evidence exists for expression of estrogen receptor β (ERβ) in human colonic mucosa. Here
we investigated the expression of the classical ER (ERα) and of four isoforms of the human …