By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ
exert opposite effects on cellular processes that include proliferation, apoptosis and …

Knockout and expression studies suggest that estrogen receptor β (ERβ) plays a prominent
role in ovarian function and pathology. Moreover, ovarian cancers are characterized by high …

Ever since the estrogen receptor (ER) β was discovered in 1996, we have been trying to
determine its value as a prognostic and/or predictive factor in breast cancer and its potential …

The prognosis in ovarian carcinoma, the most lethal of the gynecologic neoplasms, is poor
and has changed little in the last three decades. Only a small number respond to …

The role of estrogens in breast and other cancers has been extensively investigated for
many years, and historically most of these studies have focused on the hormonal regulation …

Although estrogen receptor (ER)-α is expressed in both benign and malignant ovarian
tumors, the role of ER in ovarian carcinogenesis of epithelial tumors is still unknown. In view …

The recent cloning of a second estrogen receptor (ER), designated ERβ, has prompted a
reevaluation of the role of ERs in breast cancer. We have developed and validated a real …

The discovery of ERβ in the middle of the 1990s represents a paradigm shift in our
understanding of estrogen signaling. It has turned out that estrogen action is not mediated …

Estrogen receptor (ER) expression in human lung has been understudied, particularly in
light of its potential biological importance in the female lung cancer epidemic. Reverse …

Colorectal carcinoma shows several sex‐related differences with regard to incidence,
response to chemotherapy and microsatellite instability. These differences may relate to …