Inherited thrombophilia, defined as a genetically determined tendency to develop venous
thromboembolism (VTE), contributes to the pathogenesis of~ 40% of VTE episodes. About …

The term thrombophilia includes any inherited and acquired disorders associated with an
increased tendency to venous thromboembolism (VTE). Inherited thrombophilia is one of the …

The clinical penetrance of venous thromboembolism (VTE) susceptibility genes is variable,
being lower in heterozygous carriers of factor V Leiden and prothrombin 20210A (mild …

Venous thromboembolism (VTE) susceptibility genes are widely diffuse in the general
population, but clinical penetrance of genotypes is incomplete and has variable expressivity …

Risk is defined by the World Health Organization as a probability of an adverse outcome, or
a factor that raises this probability; the identification of high-risk individuals enables targeted …

Venous thromboembolism (VTE) has important heritable components. In the past 20 years,
knowledge in this field has greatly increased with the identification of a number of gene …

The utility of laboratory investigation of relatives of individuals with inherited thrombophilia is
uncertain. To assess the risk of venous thromboembolism (VTE) among the carriers, we …

Thrombophilia is defined as a condition predisposing to the development of venous
thromboembolism (VTE) on the basis of a hypercoagu-lable state. Over the past decades …

Inherited thrombophilia can be defined as a genetically determined tendency to venous
thromboembolism. Genetic risk factors for venous thrombosis include antithrombin …

About half of all episodes of venous thromboembolism (VTE, ie deep vein thrombosis and
pulmonary embolism) are elicited by an acquired clinical risk factor, such as recent surgery …