Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is
characterized by synovial hyperplasia and progressive joint destruction. The activation of RA …

Rheumatoid arthritis (RA) is characterized by immune dysfunctions and chronic
inflammation that mainly affects diarthrodial joints. Genetics has long been surveyed in …

Rheumatoid arthritis (RA) is an autoimmune disease, characterized by chronic inflammation
of the joints with severe pain and swelling, joint damage and disability, which leads to joint …

Rheumatoid arthritis synovial fibroblasts (RASFs) are the effector cells of cartilage and bone
destruction. These cells show an'intrinsically'activated and aggressive phenotype that …

Rheumatoid arthritis is an immune-mediated disease that primarily affects diarthrodial joints.
Susceptibility and severity of this disease are influenced by nongenetic factors, such as …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Genetic and environmental factors contribute to the risk for rheumatoid arthritis (RA), with
epigenetics serving as a possible interface through which risk factors contribute to RA. High …

In its widest sense, the term epigenetics describes a range of mechanisms in genome
function that do not solely result from the DNA sequence itself. These mechanisms comprise …

Autoimmune rheumatic diseases, such as Sjögren syndrome (SS) and rheumatoid arthritis
(RA), are characterized by chronic inflammation and autoimmunity, which cause joint tissue …

Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid
arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA …