Oocyte and embryo metabolism are closely linked with their subsequent developmental
capacity. Lipids are a potent source of cellular energy, yet little is known about lipid …

To examine the effects of oxygen toxicity on embryonic development, mouse pronuclear
embryos were cultured under low oxygen conditions with or without superoxide dismutase …

Purpose We recently found that, for mouse embryos fertilized in vivo, the two-cell block could
be attenuated by adding superoxide dismutase (SOD), a scavenger of superoxide radicals …

Free radicals, once the preserve of chemists, are now recognized as playing a central role in
many biological systems. They are formed as an inevitable by-product of aerobic respiration …

In vitro culture (IVC) for porcine embryo development is inferior compared to in vivo
development because oxidative stress can be induced by the production of excessive …

L-carnitine (LC) is well known for its antioxidant activity. In this study, we explored the
potential mechanistic effects of LC supplementation on aged bovine oocytes in vitro. We …

In order to understand how in vitro culture affects embryonic quality, we analyzed survival
and global gene expression in bovine blastocysts after exposure to increased oxidative …

In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

We investigated the hypothesis that glutathione (GSH) in reproductive tract secretions (RTS)
protects the preimplantation embryo from endogenous reactive oxygen species and is …

With the nucleus as an exception, mitochondria are the only animal cell organelles
containing their own genetic information, called mitochondrial DNA (mtDNA). During oocyte …