Significance: To improve the outcomes of in vitro culture of human oocytes and embryos, the
dynamic balance and roles of reactive oxygen species (ROS) in folliculogenesis and embryo …

The objective of this study was to examine the effect of L-carnitine treatment during in vitro
maturation (IVM) of immature pig (Sus scrofa) oocytes. Specifically, the effects of L-carnitine …

STUDY QUESTION Can supplementation of media with a glutathione (GSH) donor,
glutathione ethyl ester (GEE), prior to vitrification protect the mouse oocyte from oxidative …

Oxygen radicals are involved in the in vitro block phenomenon of embryo development,
because a low oxygen tension and superoxide dismutase (SOD) have been shown to …

STUDY QUESTION Is a reduction in the oxygen tension from 5 to 2% during extended
culture from Day 3 onwards beneficial for human blastocyst development in vitro …

BACKGROUND Little is known of how the oxygen environment in the ovarian follicle affects
oocyte and embryo development, but this has an important impact on the conditions used for …

Pre-maturation aging of immature oocytes may adversely affect the fate of an oocyte.
Oxidative stress is one of the most detrimental factors affecting oocyte developmental …

The mRNA expression of five enzymes: catalase, Cu-Zn-superoxide dismutase (Cu-Zn-
SOD), Mn-superoxide dismutase (Mn-SOD), glutathione peroxidase (GPX), and γ …

Purpose The oxygen consumption rates (OCRs) in mice and cattle have been reported to
change during preimplantation embryogenesis. On the other hand, mitochondrial DNA …

The aim of the present study was to examine the effect of culture under 5 and 20% oxygen
on the development, differentiation and viability of zygotes and in-vivo-produced embryos at …