Early mammalian embryos derived from in vitro fertilization are exposed to conditions
distinct from the native oviduct‐uterine environment, including atmospheric oxygen that …

STUDY QUESTION Does in vivo aging of mouse oocytes affect mitochondrial function?
SUMMARY ANSWER Mitochondrial function was impaired in post-ovulatory in vivo-aged …

Objective To determine whether protection from oxidative stress would enhance the
development of human embryos. Design A new culture system for human IVF-ET that used …

Oxidative stress is generated by an imbalance between reactive oxygen species (ROS)
formation and cellular defense mechanisms. To reduce cellular damage caused by ROS in …

The present study aims to ascertain whether dietary supplementation with a mixture of
vitamins C and E may prevent the maternal-age-associated decrease in both the number of …

OBJECTIVE: To compare the effects of atmospheric and physiologic oxygen concentrations
on the global patterns of gene expression during mouse preimplantation development …

Background Diabetes teratogenicity seems to be related to embryonic oxidative stress and
the extent of the embryonic damage can apparently be reduced by antioxidants. We have …

Abstract Development of rabbit preimplantation embryos cultured under 20, 5 or 1% oxygen
was studied. Three-day-old morulae were cultured in a protein-free medium (BSM II …

Successful embryo and fetal development is dependent on the quality of the oocyte from
which it was derived. Several studies to date have demonstrated the link between …

Oocyte cryopreservation is imperative for assisted reproductive technologies (ART).
Although cryopreservation of oocytes at the Metaphase II has been widely used, immature …