Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …

Current views on the roles of Th1 and Th17 cells in experimental autoimmune encephalomyelitis

M El-behi, A Rostami, B Ciric - Journal of Neuroimmune Pharmacology, 2010 - Springer
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis
(EAE), are autoimmune demyelinating diseases of the central nervous system (CNS) …

Th17 cells and inflammation in neurological disorders: Possible mechanisms of action

Y Shi, B Wei, L Li, B Wang, M Sun - Frontiers in immunology, 2022 - frontiersin.org
Neurological disorders (NDs) are one of the leading causes of global death. A sustained
neuroinflammatory response has been reported to be associated with the pathogenesis of …

Th17 cell, the new player of neuroinflammatory process in multiple sclerosis

F Jadidi‐Niaragh, A Mirshafiey - Scandinavian journal of …, 2011 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of
demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …

Emerging concepts in autoimmune encephalomyelitis beyond the CD4/TH1 paradigm

H Batoulis, K Addicks, S Kuerten - Annals of Anatomy-Anatomischer …, 2010 - Elsevier
Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis
(EAE) have long been regarded as primarily T helper cell type 1-mediated diseases …

Th17 cells in autoimmune demyelinating disease

BM Segal - Seminars in immunopathology, 2010 - Springer
Recently published studies in multiple sclerosis (MS) and experimental autoimmune
encephalomyelitis (EAE) have demonstrated an association between the development of …

TH17 cytokines in autoimmune neuro-inflammation

B Becher, BM Segal - Current opinion in immunology, 2011 - Elsevier
It has been firmly established that IL-23 polarized TH17 cells are potent effectors in the
pathogenesis of experimental autoimmune encephalitomyelitis (EAE). However, the relative …

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

JM Fletcher, SJ Lalor, CM Sweeney… - Clinical & …, 2010 - academic.oup.com
Multiple sclerosis (MS) is a demyelinating inflammatory disorder of the central nervous
system (CNS), which involves autoimmune responses to myelin antigens. Studies in …

Th17 cells in central nervous system autoimmunity

C Sie, T Korn, M Mitsdoerffer - Experimental neurology, 2014 - Elsevier
Multiple sclerosis (MS) is the most important autoimmune disease of the central nervous
system (CNS). Its animal model experimental autoimmune encephalomyelitis (EAE) has …

Th17 cells, γδ T cells and their interplay in EAE and multiple sclerosis

AM McGinley, SC Edwards, M Raverdeau… - Journal of …, 2018 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis
(MS) that shares many features with the human disease. This review will focus on the role of …