Abstract Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years
ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis …

Abstract Interleukin-12 (IL-12) was the first member of the IL-12 family of cytokines to be
identified and has therefore become its eponym. It is a heterodimeric protein of two subunits …

Interleukin‐10 (IL‐10) has long been recognized to have potent and broad‐spectrum anti‐
inflammatory activity, which has been unequivocally established in various models of …

Interleukin 11 (IL11) is an elusive member of the IL6 family of cytokines. While initially
thought to be a haematopoietic and cytoprotective factor, more recent data show instead that …

Interleukin-12 (IL-12) is a heterodimeric cytokine composed of the p35 and p40 subunits. It is
produced by antigen-presenting cells and plays a critical role in host defense against …

Abstract Interleukin-15 (IL-15) is a proinflammatory cytokine involved in the development,
survival, proliferation, and activation of multiple lymphocyte lineages utilizing a variety of …

Since the cloning of interleukin (IL)-15 six years ago, there have been numerous studies
examining the molecular and cellular biology of this cytokine. IL-15 and IL-2 have similar …

IL-11 is a member of the IL-6 family of cytokines. While it was discovered over 20 years ago,
we have very little understanding of the role of IL-11 during normal homeostasis and …

This paper reviews the recent studies of interleukin-11 gene expression and regulation,
receptor and signal transduction, pharmacologic effects, and preclinical and clinical studies …

The cytokine interleukin (IL)− 6 performs a diverse portfolio of functions in normal physiology
and disease. These functions extend beyond the typical role for an inflammatory cytokine …