Bile acids, mainly ursodeoxycholic acid (UDCA) and its conjugated species
glycoursodeoxycholic acid (GUDCA) and tauroursodeoxycholic acid (TUDCA) have long …

Although mesenchymal stem cells (MSCs) are a promising cell source for regenerative
medicine, ischemia-induced endoplasmic reticulum (ER) stress induces low MSC …

Chitosan nanoparticles have been recognized as a new type of biomaterials for treatment of
spinal cord injury (SCI). To develop a novel treatment method targeted delivery injured …

Objective: Parkinson's disease (PD) is a progressive motor disease of unknown etiology.
Although neuroprotective ability of endogenous bile acid, tauroursodeoxycholic acid …

Protocatechuic acid (PCA) was first purified from green tea and has shown numerous
biological activities, including anti-apoptotic, anti-inflammatory, and anti-atherosclerotic …

After spinal cord injury (SCI), blood-spinal cord barrier (BSCB) disruption and hemorrhage
lead to blood cell infiltration and progressive secondary injuries including inflammation …

The present study used a mild contusion injury in rat spinal cord to determine that
thymoquinone reduces inflammatory response, oxidative stress and apoptosis in a spinal …

Tauroursodeoxycholic acid (TUDCA), an endogenous bile acid, modulates cell death by
interrupting classic pathways of apoptosis. Amyloid-β (Aβ) peptide has been implicated in …

Objectives Systemic administration of lipopolysaccharide induces neuroinflammation
leading to cognitive deficit and memory impairment. Herein, we investigated the effects of p …

Tauroursodeoxycholic acid (TUDCA), a hydrophilic bile acid, is a strong modulator of
apoptosis in both hepatic and nonhepatic cells, and appears to function by inhibiting …