Carnosine attenuates early brain injury through its antioxidative and anti-apoptotic effects in a rat experimental subarachnoid hemorrhage model
Z Zhang, B Sun, M Yang, D Li, J Fang… - Cellular and Molecular …, 2015 - Springer
Abstract Carnosine (β-alanyl-l-histidine) has been demonstrated to provide antioxidative
and anti-apoptotic roles in the animal of ischemic brain injuries and neurodegenerative …
and anti-apoptotic roles in the animal of ischemic brain injuries and neurodegenerative …
Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS)-induced neuroinflammation by targeting TLR4/NFκB, autophagy, inflammation and …
N Jamali-Raeufy, F Alizadeh, Z Mehrabi… - Metabolic brain …, 2021 - Springer
Acetyl-L-carnitine has been shown to exert neuroprotection against neurodegenerative
diseases. The present study was performed to evaluate neuroprotection effects of acetyl-L …
diseases. The present study was performed to evaluate neuroprotection effects of acetyl-L …
Repetitive mild traumatic brain injury-induced neurodegeneration and inflammation is attenuated by acetyl-L-carnitine in a preclinical model
MI Hiskens, KM Li, AG Schneiders… - Frontiers in …, 2023 - frontiersin.org
Repetitive mild traumatic brain injuries (rmTBI) may contribute to the development of
neurodegenerative diseases through secondary injury pathways. Acetyl-L-carnitine (ALC) …
neurodegenerative diseases through secondary injury pathways. Acetyl-L-carnitine (ALC) …
Homocysteine aggravates cortical neural cell injury through neuronal autophagy overactivation following rat cerebral ischemia-reperfusion
Y Zhao, G Huang, S Chen, Y Gou, Z Dong… - International journal of …, 2016 - mdpi.com
Elevated homocysteine (Hcy) levels have been reported to be involved in neurotoxicity after
ischemic stroke. However, the underlying mechanisms remain incompletely understood to …
ischemic stroke. However, the underlying mechanisms remain incompletely understood to …
Aucubin promoted neuron functional recovery by suppressing inflammation and neuronal apoptosis in a spinal cord injury model
S Xiao, N Zhong, Q Yang, A Li, W Tong, Y Zhang… - International …, 2022 - Elsevier
Background Spinal cord injury (SCI) can cause severe motor impairment. Post-SCI treatment
has focused primarily on secondary injury, with neuroinflammation and neuronal apoptosis …
has focused primarily on secondary injury, with neuroinflammation and neuronal apoptosis …
Neuroprotective effect of licochalcone A against oxygen‐glucose deprivation/reperfusion in rat primary cortical neurons by attenuating oxidative stress injury and …
X Liu, Y Ma, X Wei, T Fan - Journal of cellular biochemistry, 2018 - Wiley Online Library
Perinatal hypoxic‐ischemic encephalopathy (HIE) is a leading cause of neonatal death and
neurological disability. Oxidative stress and neuroinflammation are typical pathogenic …
neurological disability. Oxidative stress and neuroinflammation are typical pathogenic …
The effects of N-acetyl-cysteine and acetyl-L-carnitine on neural survival, neuroinflammation and regeneration following spinal cord injury
A Karalija, LN Novikova, PJ Kingham, M Wiberg… - Neuroscience, 2014 - Elsevier
Traumatic spinal cord injury induces a long-standing inflammatory response in the spinal
cord tissue, leading to a progressive apoptotic death of spinal cord neurons and glial cells …
cord tissue, leading to a progressive apoptotic death of spinal cord neurons and glial cells …
Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats
JD Figueroa, K Cordero, K Baldeosingh… - Journal of …, 2012 - liebertpub.com
Currently, few interventions have been shown to successfully limit the progression of
secondary damage events associated with the acute phase of spinal cord injury (SCI) …
secondary damage events associated with the acute phase of spinal cord injury (SCI) …
Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury
JW Wang, HD Wang, ZX Cong, XM Zhou, JG Xu… - Journal of Surgical …, 2014 - Elsevier
Background A wealth of evidence has suggested that oxidative stress is involved in the
secondary brain injury after traumatic brain injury (TBI). Recently, numerous in vivo and in …
secondary brain injury after traumatic brain injury (TBI). Recently, numerous in vivo and in …
Taurine reduces inflammatory responses after spinal cord injury
Y Nakajima, K Osuka, Y Seki, RC Gupta… - Journal of …, 2010 - liebertpub.com
Taurine has multiple functions in the central nervous system (CNS), serving as an
osmoregulator, antioxidant, inhibitory neuromodulator, and regulator of intracellular Ca2+ …
osmoregulator, antioxidant, inhibitory neuromodulator, and regulator of intracellular Ca2+ …