Spinal cord injury (SCI) is a severe nervous system disease that may lead to lifelong
disability. Studies have shown that autophagy plays a key role in various diseases; however …

Modulation of N-acylethanolamine-hydrolyzing acid amidase (NAAA) represents a potential
alternative strategy in the treatment of neuroinflammation. Recent studies showed that …

Mitochondrial dysfunction has been deeply implicated in the pathogenesis of several
neurodegenerative diseases. Thus, to keep a healthy mitochondrial population, a balanced …

After spinal cord injury (SCI), blood-spinal cord barrier (BSCB) disruption results in
secondary injury including apoptotic cell death of neurons and oligodendrocytes, thereby …

Background Neuronal apoptosis and inflammation are the key pathogenic features of
secondary brain injury, which results in the neurological impairment that traumatic brain …

Fucoidan, a natural sulfated polysaccharide, displays various biological activities including
antioxidant properties. We examined the neuroprotective effect of fucoidan against transient …

Background: Hyodeoxycholic acid (HDCA) is a natural secondary bile acid with enormous
pharmacological effects, such as modulating inflammation in neuron. However, whether …

D-galactose (GAL) has been used as an animal model for brain aging and antiaging studies.
GAL stimulates oxidative stress in several tissues including brain. Carnosine (CAR; β-alanil …

Background Increasing evidence demonstrate N-acetylcysteine amide (NACA) provides
neuroprotection and attenuated oxidative stress in rats following traumatic brain injury (TBI) …

Aims Usually, spinal cord injury (SCI) develops into a glial scar containing extracellular
matrix molecules including chondroitin sulfate proteoglycans (CSPG s). Chondroitinase ABC …