Ruxolitinib attenuates secondary injury after traumatic spinal cord injury
ZY Qian, RY Kong, S Zhang, BY Wang… - Neural Regeneration …, 2022 - journals.lww.com
Excessive inflammation post-traumatic spinal cord injury (SCI) induces microglial activation,
which leads to prolonged neurological dysfunction. However, the mechanism underlying …
which leads to prolonged neurological dysfunction. However, the mechanism underlying …
Neuroprotective effects of thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis
OBJECTIVE Ischemia-reperfusion (I/R) injury of the spinal cord following thoracoabdominal
aortic surgery remains the most devastating complication, with a life-changing impact on the …
aortic surgery remains the most devastating complication, with a life-changing impact on the …
Neuroprotective effects of carnosic acid on neuronal cells under ischemic and hypoxic stress
CW Hou, YT Lin, YL Chen, YH Wang… - Nutritional …, 2012 - Taylor & Francis
Ischemia/hypoxia induces oxidative stress which is associated with neurodegenerative
diseases. The present study investigated protective mechanism of carnosic acid (CA) on …
diseases. The present study investigated protective mechanism of carnosic acid (CA) on …
Tauroursodeoxycholic acid produces antidepressant‐like effects in a chronic unpredictable stress model of depression via attenuation of neuroinflammation, oxido …
XU Lu, RR Yang, JL Zhang, P Wang… - Fundamental & …, 2018 - Wiley Online Library
Depression is a common psychiatric disorder with heavy economic and social burdens.
Searching new agents with better antidepressant‐like activities is of great significance for …
Searching new agents with better antidepressant‐like activities is of great significance for …
Curcumin improves the recovery of motor function and reduces spinal cord edema in a rat acute spinal cord injury model by inhibiting the JAK/STAT signaling pathway
J Zu, Y Wang, G Xu, J Zhuang, H Gong, J Yan - Acta histochemica, 2014 - Elsevier
Curcumin, a yellow pigment extracted from Carcuma longa, has been demonstrated to have
extensive pharmacological activity in various studies, and it exhibits protective effects on …
extensive pharmacological activity in various studies, and it exhibits protective effects on …
Therapeutic effect of apocynin through antioxidant activity and suppression of apoptosis and inflammation after spinal cord injury
Y Sun, F Gong, J Yin, X Wang… - Experimental and …, 2017 - spandidos-publications.com
Spinal cord injury (SCI) is a devastating condition affecting hundreds of thousands of people
worldwide annually. SCI results in activation of the inflammatory response and apoptosis …
worldwide annually. SCI results in activation of the inflammatory response and apoptosis …
Salvianolic acid B attenuates spinal cord ischemia-reperfusion–induced neuronal injury and oxidative stress by activating the extracellular signal–regulated kinase …
J Fu, H Fan, Z Guo, Z Wang, X Li, J Li, G Pei - journal of surgical research, 2014 - Elsevier
Abstract Background Salvianolic acid B (SalB), the main bioactive compound isolated from
the traditional Chinese medicinal herb broad Radix Salviae Miltiorrhizae exerts a spectrum …
the traditional Chinese medicinal herb broad Radix Salviae Miltiorrhizae exerts a spectrum …
N-Acetyl-l-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice
N Hegdekar, MM Lipinski, C Sarkar - Scientific reports, 2021 - nature.com
Traumatic brain injury (TBI) is a major cause of mortality and long-term disability around the
world. Even mild to moderate TBI can lead to lifelong neurological impairment due to acute …
world. Even mild to moderate TBI can lead to lifelong neurological impairment due to acute …
Histone deacetylase inhibitor trichostatin A ameliorated endotoxin‐induced neuroinflammation and cognitive dysfunction
CH Hsing, SK Hung, YC Chen, TS Wei… - Mediators of …, 2015 - Wiley Online Library
Excessive production of cytokines by microglia may cause cognitive dysfunction and long‐
lasting behavioral changes. Activating the peripheral innate immune system stimulates …
lasting behavioral changes. Activating the peripheral innate immune system stimulates …
Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury
H Wang, XM Zhou, LY Wu, GJ Liu, WD Xu… - Journal of …, 2020 - Springer
Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …