Wallerian degeneration occurs after peripheral nerve injury and provides a beneficial
microenvironment for nerve regeneration. Our previous study demonstrated that ascorbic …

Objective: The study was aimed to investigate whether the neuroprotective role of curcumin
is associated with regulation of autophagy. Methods: Rat spinal cord injury (SCI) models …

Histone deacetylases (HDAC) inhibitors including valproic acid (VPA) have emerged as a
promising therapeutic intervention in neurological disorders. We investigated the levels of …

Inflammation has been known to play an important role in the pathogenesis after spinal cord
injury (SCI). Microglia are activated after injury and produce a variety of proinflammatory …

Scutellarin, a bioactive flavone isolated from Scutellaria baicalensis, has anti-inflammatory,
anti-neurotoxic, anti-apoptotic and anti-oxidative effects and has been used to treat …

Spinal cord injury (SCI) is a serious clinical situation without any effective therapy to date.
Traumatic SCI triggers a complex pathological process including inflammatory response and …

BACKGROUND CONTEXT Curcumin has anti-inflammatory and antioxidant activities.
OBJECTIVE This study aimed to investigate the effects of curcumin on the histological …

Ascorbic acid (AA) is an essential micronutrient that has been safely used in the clinic for
many years. The present study indicates that AA has an unexpected function in facilitating …

Abstract Salvianolic acid B (Sal B), a bioactive compound isolated from the Chinese
medicinal herb danshen, is commonly used for the prevention and treatment of …

The purpose of this study is to investigate the protective effect of dehydrocostuslactone
(DHL) on PC12 cells injury induced by oxygen and glucose deprivation/reperfusion (OGD/R) …