Platelet-targeted pharmacologic treatments as anti-cancer therapy

P Gresele, S Momi, M Malvestiti… - Cancer and Metastasis …, 2017 - Springer
Platelets act as multifunctional cells participating in immune response, inflammation, allergy,
tissue regeneration, and lymphoangiogenesis. Among the best-established aspects of a role …

Anti-platelet treatments in cancer: Basic and clinical research

P Gresele, M Malvestiti, S Momi - Thrombosis Research, 2018 - Elsevier
Over the past few decades the central role that platelets play in cancer development and
progression, and especially in metastasis, has been elucidated. The molecular mechanisms …

Platelets in cancer

E Mammadova-Bach, P Mangin, F Lanza… - …, 2015 - thieme-connect.com
Platelets are well-known for their major role in primary hemostasis and thrombosis. Cancer
patients frequently manifest thrombotic events and present abnormalities in blood …

Platelets in cancer development and diagnosis

A Contursi, R Grande, M Dovizio… - Biochemical Society …, 2018 - portlandpress.com
Platelets are involved in the development and progression of cancer through several
mechanisms. Platelet activation at the site of tissue damage contributes to the initiation of a …

Platelets: the point of interconnection among cancer, inflammation and cardiovascular diseases

M Camilli, G Iannaccone, G La Vecchia… - Expert review of …, 2021 - Taylor & Francis
Introduction The association between thrombosis, cancer and inflammation is well-
established. Platelets play a major role in atherosclerosis, inflammation and immune …

Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting

A Contursi, A Sacco, R Grande, M Dovizio… - Cellular and molecular …, 2017 - Springer
Platelets are anucleated cells that circulate in the blood as sentinels of tissue integrity. In
fact, they are rich in a plethora of proteins and other factors stored in different granules which …

[HTML][HTML] The platelet contribution to cancer progression

NM Bambace, CE Holmes - Journal of thrombosis and haemostasis, 2011 - Elsevier
Traditionally viewed as major cellular components in hemostasis and thrombosis, the
contribution of platelets to the progression of cancer is an emerging area of research …

Involvement of platelets in cancers

D Mege, M Aubert, R Lacroix… - … in thrombosis and …, 2019 - thieme-connect.com
Cancer-related venous thromboembolism (VTE) is frequent and constitutes the second
leading cause of death in patients with cancer. High platelet count is one of independent …

The role of platelet activation in tumor metastasis

L Borsig - Expert review of anticancer therapy, 2008 - Taylor & Francis
Platelets are highly reactive components of the circulatory system, which exert not only
haemostatic activity but also contribute to the modulation of various pathological conditions …

The role of platelets in tumor growth, metastasis, and immune evasion

Z Li, B Riesenberg, A Metelli, A Li, BX Wu - Platelets, 2019 - Elsevier
The successful growth and dissemination of tumors are dependent on a multitude of cancer
cell intrinsic and extrinsic factors. A growing body of work, both observational and …