Background To prevent iatrogenic damage, transfusions of red blood cells should be
avoided. For this, specific and reliable transfusion triggers must be defined. To date, the …

OBJECT There is limited literature available to guide transfusion practices for patients with
severe traumatic brain injury (TBI). Recent studies have shown that maintaining a higher …

In the previous issue of Critical Care, Sekhon and colleagues report that mean 7-day
hemoglobin concentration< 90 g/l was associated with increased mortality among patients …

Rationale. By reducing cerebral oxygen delivery, anemia may aggravate traumatic brain
injury (TBI) secondary insult. This study evaluated the impact of anemia and blood …

Purpose We aimed to evaluate the association between transfusion practices and clinical
outcomes in patients with traumatic brain injury. Material and methods We conducted a …

Robertson et al.(JAMA 2014; 312: 36-47) investigated the effects of two different thresholds
of hemoglobin (Hb) to guide red blood cells transfusions (RBCT; 7 g/dL vs. 10 g/dL) in …

BACKGROUND Blood transfusion strategies among patients with critical illness use a
restrictive hemoglobin threshold. However, among patients with head injury, no outcome …

Both severe anemia and red blood-cell transfusion may negatively influence clinical
outcome in neurocritical patients. Acceptance of low hemoglobin concentrations may be …

Background: The effect of blood component ratios on the survival of patients with traumatic
brain injury (TBI) has not been studied. Methods: A database of patients transfused in the …

Currently, there is insufficient evidence to make strong recommendations regarding which
hemoglobin threshold to use as a transfusion trigger in critically-ill patients with TBI. There is …