Mammalian spermatogenesis requires a stem cell pool, a period of amplification of cell
numbers, the completion of reduction division to haploid cells (meiosis), and the …

Spermatogenesis is a complex biological process of cellular transformation that produces
male haploid germ cells from diploid spermatogonial stem cells. This process has been …

Mammalian spermatogenesis is an elaborately organized differentiation process, starting
with diploid spermatogonia, which include germ-line stem cells, and ending with haploid …

The purpose of this chapter is to provide a comprehensive overview of spermatogenesis and
the various steps involved in the development of the male gamete, including cellular …

In recent years, extraordinary progress has been made in a broad range of reproductive
technologies, including spermatogonial transplantation in the male. However, effective …

Retinoic acid (RA) directs the sequential, but distinct, programs of spermatogonial
differentiation and meiotic differentiation that are both essential for the generation of …

The production of spermatozoa relies on a pool of spermatogonial stem cells (SSCs), formed
in infancy from the differentiation of their precursor cells, the gonocytes. Throughout adult …

Spermatogenesis is a complex process involving mitotic cell division, meiosis and the
process of spermiogenesis. The regulation of spermatogenesis involves both endocrine and …

Spermatogenesis is contingent upon hormones and growth factors acting through endocrine
and paracrine pathways either in vivo or in vitro. Sertoli cells (SCs) furnish essential factors …

Most organisms consist of two cell lineages—somatic cells and germ cells. The former are
required for the current generation, and the latter create offspring. Male and female germ …