[HTML][HTML] Immunogenicity and reactogenicity in Q fever vaccine development

AP Fratzke, EJ van Schaik, JE Samuel - Frontiers in Immunology, 2022 - frontiersin.org
Coxiella burnetii is an obligate intracellular bacterium which, in humans, causes the disease
Q fever. Although Q fever is most often a mild, self-limiting respiratory disease, it can cause a …

[HTML][HTML] Vaccination against Q fever for biodefense and public health indications

S Ruiz, DN Wolfe - Frontiers in Microbiology, 2014 - frontiersin.org
Coxiella burnetii is the etiological agent of Q fever, a disease that is often spread to humans
via inhalational exposure to the bacteria from contaminated agricultural sources. Outbreaks …

Components of protective immunity

G Zhang, Y Zhang, JE Samuel - … and New Perspectives in Research of the …, 2012 - Springer
Coxiella burnetii is an obligate intracellular bacterium that causes a worldwide zoonotic
disease, Q fever. Since C. burnetii infection could develop into severe chronic disease in …

Q fever–immune responses and novel vaccine strategies

P Redden, K Parker, S Henderson, P Fourie… - Future …, 2023 - Future Medicine
Q fever is a zoonotic disease caused by the bacterium Coxiella burnetii. It is an occupational
risk for employees of animal industries and is associated with contact with wildlife and …

Q fever vaccine development: current strategies and future considerations

CM Long - Pathogens, 2021 - mdpi.com
Q fever is a zoonotic disease caused by the intracellular pathogen Coxiella burnetii. This
disease typically manifests as a self-limiting, febrile illness known as acute Q fever. Due to …

Q fever immunology: the quest for a safe and effective vaccine

G Sam, J Stenos, SR Graves, BHA Rehm - npj Vaccines, 2023 - nature.com
Q fever is an infectious zoonotic disease, caused by the Gram-negative bacterium Coxiella
burnetii. Transmission occurs from livestock to humans through inhalation of a survival form …

[PDF][PDF] Soluble antigens derived from Coxiella burnetii elicit protective immunity in three animal models without inducing hypersensitivity

AE Gregory, EJ van Schaik, AP Fratzke… - Cell Reports …, 2021 - cell.com
Q fever is caused by the intracellular bacterium Coxiella burnetii, for which there is no
approved vaccine in the United States. A formalin-inactivated whole-cell vaccine (WCV) from …

[HTML][HTML] Preclinical animal models for Q fever vaccine development

M Tesfamariam, P Binette, CM Long - Frontiers in Cellular and …, 2022 - frontiersin.org
Coxiella burnetii is a zoonotic pathogen responsible for the human disease Q fever. While
an inactivated whole cell vaccine exists for this disease, its widespread use is precluded by …

Adaptive immunity to the obligate intracellular pathogen Coxiella burnetii

JG Shannon, RA Heinzen - Immunologic research, 2009 - Springer
Coxiella burnetii is an obligate intracellular bacterial pathogen that causes the zoonosis Q
fever. While an effective whole-cell vaccine (WCV) against Q fever exists, the vaccine has …

Vaccines against Coxiella infection

G Zhang, JE Samuel - Expert review of vaccines, 2004 - Taylor & Francis
Coxiella burnetii is an obligate intracellular bacterium that causes a worldwide zoonotic
disease, Q fever. Since C. burnetii infection is an occupational hazard and could develop …