Neuropathic pain refers to a specific pain syndrome characterized by pain and sensory
abnormalities in body parts that have lost their normal peripheral innervation or sensory …

For patients suffering with chronic neuropathic pain the need for suitable novel therapies is
imperative. Over recent years a contributing factor for the lack of development of new …

Neuropathic pain represents a series of relatively uncommon chronic pain conditions,
caused by lesions or dysfunctions of peripheral or central afferent pathways in the nervous …

While it may be convenient to categorize neuropathic pain syndromes on the basis of
anatomical distribution or disease state (eg, diabetic neuropathy, radiculopathy, postherpetic …

Peripheral neuropathic pain, that clinical pain syndrome associated with lesions to the
peripheral nervous system, is characterized by positive and negative symptoms. Positive …

Pain usually occurs when a potential tissue-damaging stimulus excites peripheral
nociceptive afferents. When a noxious stimulus activates receptors in skin, muscle, or joint …

Neuropathic pains refer to a heterogenous group of pain conditions characterised by lesion
or dysfunction of the normal sensory pathways. Clinical characteristics include: delayed …

The paper addresses issues related to the clinical relevance of currently employed animal
models of neuropathic pain and our inability to translate clinical symptoms and signs into …

Neuropathic pain syndromes—pain after a lesion or disease of the peripheral or central
nervous system—are clinically characterized by spontaneous and evoked types of pain …

Neuropathic pain is caused by a lesion or disease of the somatosensory system, including
peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7–10% of the …