Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. To date, the
molecular mechanisms of DN remain largely unclear. The present study aimed to identify …
molecular mechanisms of DN remain largely unclear. The present study aimed to identify …
[HTML][HTML] Identification of novel key molecular signatures in the pathogenesis of experimental diabetic kidney disease
M Diao, Y Wu, J Yang, C Liu, J Xu, H Jin… - Frontiers in …, 2022 - frontiersin.org
Diabetic kidney disease (DKD) is a long-term major microvascular complication of
uncontrolled hyperglycemia and one of the leading causes of end-stage renal disease …
uncontrolled hyperglycemia and one of the leading causes of end-stage renal disease …
[HTML][HTML] Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice
T Wei, L Zhao, J Jia, H Xia, Y Du, Q Lin, X Lin, X Ye… - Scientific reports, 2015 - nature.com
Diabetic nephropathy (DN) is one of the lethal manifestations of diabetic systemic
microvascular disease. Elucidation of characteristic metabolic alterations during diabetic …
microvascular disease. Elucidation of characteristic metabolic alterations during diabetic …
[HTML][HTML] Multi-omics analysis of diabetic nephropathy reveals potential new mechanisms and drug targets
Q Sha, J Lyu, M Zhao, H Li, M Guo, Q Sun - Frontiers in genetics, 2020 - frontiersin.org
Diabetic nephropathy (DN) is one of the most common diabetic complications, which is the
major course of end-stage renal disease (ESRD). However, the systematical molecular …
major course of end-stage renal disease (ESRD). However, the systematical molecular …
[HTML][HTML] Dynamic phenotypes and molecular mechanisms to understand the pathogenesis of diabetic nephropathy in two widely used animal models of type 2 …
Y Liu, H Huang, R Gao, Y Liu - Frontiers in cell and developmental …, 2020 - frontiersin.org
Objective We aimed to characterize the pathogenesis of diabetic nephropathy (DN) in two
commonly used type 2 diabetes mellitus (T2DM) animal models and explore the preliminary …
commonly used type 2 diabetes mellitus (T2DM) animal models and explore the preliminary …
[HTML][HTML] Pathophysiologic mechanisms and potential biomarkers in diabetic kidney disease
CY Jung, TH Yoo - Diabetes & Metabolism Journal, 2022 - ncbi.nlm.nih.gov
Although diabetic kidney disease (DKD) remains the leading cause of end-stage kidney
disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD …
disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD …
[HTML][HTML] Identification of novel biomarker for early detection of diabetic nephropathy
Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus.
After development of DN, patients will progress to end-stage renal disease, which is …
After development of DN, patients will progress to end-stage renal disease, which is …
[HTML][HTML] What's new in the molecular mechanisms of diabetic kidney disease: recent advances
K Watanabe, E Sato, E Mishima, M Miyazaki… - International journal of …, 2022 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …
[HTML][HTML] Insight into the Molecular Mechanism of Diabetic Kidney Disease and the Role of Metformin in Its Pathogenesis
M Kleibert, P Zygmunciak, K Łakomska, K Mila… - International Journal of …, 2023 - mdpi.com
Diabetic kidney disease (DKD) is one of the leading causes of death among patients
diagnosed with diabetes mellitus. Despite the growing knowledge about the pathogenesis of …
diagnosed with diabetes mellitus. Despite the growing knowledge about the pathogenesis of …
[HTML][HTML] Serum metabolomics benefits discrimination kidney disease development in type 2 diabetes patients
X Peng, X Wang, X Shao, Y Wang, S Feng… - Frontiers in …, 2022 - frontiersin.org
Background: Diabetic kidney disease (DKD) is the primary cause of end-stage renal
disease, raising a considerable burden worldwide. Recognizing novel biomarkers by …
disease, raising a considerable burden worldwide. Recognizing novel biomarkers by …