Quantitative Metabolomic Profiling of Serum, Plasma, and Urine by 1H NMR Spectroscopy Discriminates between Patients with Inflammatory Bowel Disease and …

R Schicho, R Shaykhutdinov, J Ngo… - Journal of proteome …, 2012 - ACS Publications
Serologic biomarkers for inflammatory bowel disease (IBD) have yielded variable
differentiating ability. Quantitative analysis of a large number of metabolites is a promising …

Urinary NMR metabolomic profiles discriminate inflammatory bowel disease from healthy

NS Stephens, J Siffledeen, X Su… - Journal of Crohn's …, 2013 - academic.oup.com
Background and aims: Inflammatory bowel disease, a chronic inflammation of the intestinal
tract, presents in two variations, Ulcerative Colitis (UC) and Crohn's disease (CD). Given that …

Serum metabolic profiling in inflammatory bowel disease

HRT Williams, JD Willsmore, IJ Cox, DG Walker… - Digestive diseases and …, 2012 - Springer
Background The inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative
colitis (UC), are chronic inflammatory conditions of the gastrointestinal tract whose …

Quantitative Metabolomic Profiling of Serum and Urine in DSS-Induced Ulcerative Colitis of Mice by 1H NMR Spectroscopy

R Schicho, A Nazyrova, R Shaykhutdinov… - Journal of proteome …, 2010 - ACS Publications
Quantitative profiling of a large number of metabolic compounds is a promising method to
detect biomarkers in inflammatory bowel diseases (IBD), such as ulcerative colitis (UC). We …

Characterization of inflammatory bowel disease with urinary metabolic profiling

HRT Williams, JI Cox, DG Walker… - Official journal of the …, 2009 - journals.lww.com
OBJECTIVES: Distinguishing between the inflammatory bowel disease (IBD), Crohn's
disease (CD), and ulcerative colitis (UC) is important for both management and prognostic …

Plasma nuclear magnetic resonance metabolomics discriminates between high and low endoscopic activity and predicts progression in a prospective cohort of …

F Probert, A Walsh, M Jagielowicz, T Yeo… - Journal of Crohn's …, 2018 - academic.oup.com
Abstract Background and Aims Endoscopic assessment of ulcerative colitis [UC] is one of
the most accurate measures of disease activity, but frequent endoscopic investigations are …

[HTML][HTML] Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases

T Dawiskiba, S Deja, A Mulak, A Ząbek… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To evaluate the utility of serum and urine metabolomic analysis in diagnosing and
monitoring of inflammatory bowel diseases (IBD). METHODS: Serum and urine samples …

Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome

G Le Gall, SO Noor, K Ridgway, L Scovell… - Journal of proteome …, 2011 - ACS Publications
1H NMR spectroscopy of aqueous fecal extracts has been used to investigate differences in
metabolic activity of gut microbiota in patients with ulcerative colitis (UC)(n= 13), irritable …

Rapid and noninvasive metabonomic characterization of inflammatory bowel disease

JR Marchesi, E Holmes, F Khan… - Journal of proteome …, 2007 - ACS Publications
Inflammatory bowel diseases (IBD) including Crohn's disease (CD) and ulcerative colitis
(UC) have a major impact on the health of individuals and populations. Accurate diagnosis …

Alterations in lipid, amino acid, and energy metabolism distinguish Crohn's disease from ulcerative colitis and control subjects by serum metabolomic profiling

EA Scoville, MM Allaman, CT Brown, AK Motley… - Metabolomics, 2018 - Springer
Introduction Biomarkers are needed in inflammatory bowel disease (IBD) to help define
disease activity and identify underlying pathogenic mechanisms. We hypothesized that …