Ferroptosis is a non-traditional form of regulated cell death, characterized by iron overload
and lipid peroxidation. Exploration of ferroptosis in chronic kidney disease (CKD) has been …

The bidirectional causality between kidney injury and inflammation remains an area of
unexpected discoveries. The last decade unraveled the molecular mechanisms of sterile …

Acute kidney injury (AKI) is a heterogeneous group of critical disease conditions with high
incidence and mortality. Vasoconstriction, oxidative stress, apoptosis, and inflammation are …

The pathogenesis of acute renal failure has been attributed to persistent vasoconstriction
and leukocyte-endothelial interactions, resulting in inflammation and compromise of local …

Apoptosis of tubular epithelial cells contributes to the tubular atrophy that accompanies
diabetic nephropathy. Reactive oxygen species (ROS) promote tubular apoptosis, but the …

Pyroptosis is a novel inflammatory form of regulated cell death (RCD), characterized by cell
swelling, membrane rupture, and pro-inflammatory effects. It is recognized as a potent …

Apoptosis in glomerular sclerosis. Glomerulosclerosis is characterized by progressive
extracellular matrix accumulation and glomerular cell loss. The role of glomerular cell …

In contrast to apoptosis and autophagy, necrotic cell death was considered to be a random,
passive cell death without definable mediators. However, this dogma has been challenged …

Necrosis has been defined as a type of cell death that lacks the features of apoptosis and
autophagy, and is usually considered to be uncontrolled. Recent research suggests …

The cellular and molecular tools of modern science have provided critical new insights into
the roles of apoptosis, oxidant and iron-mediated injury, endothelial changes, regeneration …